Jonas Demeulemeester

Group Leader at The Francis Crick Institute

Leuven, Flemish Brabant, Belgium
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Summary

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Jonas Demeulemeester is a biochemist and computational biologist with ~10 years of experience leading integrative genomics research at VIB–KU Leuven, where he heads the Integrative Genomics Lab focused on single-molecule and single-cell multi-omics. He blends wet‑lab insight from a PhD on retroviral integration and drug discovery with postdoctoral expertise in pan‑cancer and single‑cell omics to build novel computational pipelines that illuminate tumour heterogeneity and evolution. His group pushes emerging technologies to spatial and time‑series resolutions and interrogates understudied phenomena such as extrachromosomal DNA, RNA editing, and translation in cancer. Known for translating large-scale ICGC/PCAWG analyses into tractable methods, he connects methodological rigor with biological curiosity to tackle hard problems in tumour dynamics. Based in Leuven, Belgium, he retains an uncommon mix of structural virology background and large‑scale cancer genomics that informs both tool development and hypothesis‑driven discovery.
code10 years of coding experience
job7 years of employment as a software developer
bookDoctor of Philosophy (Ph.D.), Biomedical Sciences, Doctor of Philosophy (Ph.D.), Biomedical Sciences at University of Leuven
bookHigh School, Science and Mathematics, High School, Science and Mathematics at Don Bosco Haacht ASO
languagesEnglish, Dutch, French, German
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Stackoverflow

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Github Skills (35)

guppy10
modular10
describe10
python10
r-package10
linux10
hpc10
cpp10
pepper8
variants7
margin7
sequence6
genome6
pytorch6
genomics5

Programming languages (5)

DockerfileC++RCythonPython

Github contributions (5)

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jdemeul/ascat

Aug 2018 - Aug 2023

Contributions:2 PRs, 8 pushes, 1 branch in 5 years
r-packagecopy-numberrstats
jdemeul/Dockerfiles

Jul 2021 - Mar 2023

Repo containing docker files forming the base of various pipelines
Contributions:5 reviews, 52 commits, 7 PRs in 1 year 7 months
pipelinesdockerdocker-files
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Jonas Demeulemeester - Group Leader at The Francis Crick Institute