Jonathan Dursi is a Senior Solutions Architect who combines over two decades of deep technical R&D experience with national-scale program leadership at the intersection of AI, life sciences, and advanced computing infrastructure. He has moved seamlessly between academia, government and industry—shaping Canada’s research computing strategy as Compute Canada’s first CTO, building the federated CanDIG genomics platform that seeded a $300M cancer network, and now advising national R&D customers at NVIDIA on $300M+ procurements. Jonathan is as comfortable redesigning distributed auth and federated bioinformatics algorithms as he is coordinating 150+ FTE operations and running multi-year stakeholder engagements. He contributes hands-on to open-source scientific tooling (notably improving nanopore methylation analysis in nanopolish) and repeatedly turns prototype research into production-grade, standards-driving systems. Colleagues rely on him for bridging technical depth with policy, training, and strategic planning to deliver real-world impact from complex research problems.
12 years of coding experience
13 years of employment as a software developer
B. Sc. Math Physics Computer Science, B. Sc. Math Physics Computer Science at Saint Mary's University
M. Sc. Physics Astrophysics Computational Science, M. Sc. Physics Astrophysics Computational Science at Queen's University
Ph.D. Astrophysics, Ph.D. Astrophysics at University of Chicago
Contributions:28 commits, 7 PRs, 3 comments in 10 months
Contributions summary:Jonathan primarily focused on modifying and optimizing the `nanopolish` codebase, which includes signal-level algorithms for MinION data. Their contributions centered on refining the core algorithms, particularly regarding pore models and k-mer handling. They implemented changes to improve the accuracy of methylation analysis by recalibrating reads and refining model scoring. The user's work impacted the core functionality of the software, with a focus on improving the accuracy of the methylation analysis tools.
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