Joshua Shapiro

Senior Data Scientist, Childhood Cancer Data Lab

Greater Philadelphia United States
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Summary

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Joshua Shapiro is a Senior Data Scientist at the Childhood Cancer Data Lab with 15 years of experience applying genomics, statistical genetics, and bioinformatics to large-scale genomic datasets. He holds a PhD in Evolutionary Genetics and blends deep expertise in association/linkage mapping, population genetics, and evolutionary biology with practical skills in next-generation sequence analysis and custom assay design. Joshua transitioned from academia—where he taught genomics, bioinformatics, and biostatistics and led research at Princeton and Bryn Mawr—to mission-driven data science focused on childhood cancer. He is comfortable moving between code, statistical methods, and wet-lab insight, which helps translate complex genomic signals into clinically relevant analyses. Based in Greater Philadelphia, he combines rigorous research training with hands-on data engineering to support reproducible, scalable analyses for translational research. An often-overlooked strength is his teaching background, which he leverages to communicate results clearly to both scientific and nontechnical stakeholders.
code15 years of coding experience
job17 years of employment as a software developer
bookWest Windsor-Plainsboro High School
bookPhD, Evolutionary Genetics, PhD, Evolutionary Genetics at University of Chicago
bookBA, Biology, BA, Biology at Williams College
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Stackoverflow

Stats
196reputation
156kreached
7answers
2questions
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Github Skills (109)

python10
spatial-transcriptomics10
gene-expression10
atlas10
nextflow10
biodata10
differential-expression10
portal10
bioinformatics10
r9
rocker9
package-management9
notebook9
tidyverse9
reproducible-research9

Programming languages (12)

DockerfileRC++ShellRustCJavaScriptHTML

Github contributions (5)

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AlexsLemonade/OpenScPCA-nf

Apr 2024 - Mar 2025

A workflow for running OpenScPCA analysis modules
Contributions:3 releases, 67 reviews, 115 PRs in 11 months
A collection of modules that are combined into 1-5 day workshops on computational topics for the childhood cancer research community.
Contributions:8 releases, 540 reviews, 903 commits in 3 years 4 months
pythondaymachine-learningcancerchildhood
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Joshua Shapiro - Senior Data Scientist, Childhood Cancer Data Lab