Keren Xu

Senior Bioinformatics Scientist

Los Angeles, California, United States
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Summary

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Senior
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Keren Xu is a Senior Bioinformatics Scientist at Tempus AI with eight years of experience bridging epidemiology and genomics, and a PhD from USC focused on variant discovery and (epi)genome-wide association studies for hematologic malignancies. She combines strong computational skills—building pipelines for germline/somatic variant calling, structural variation, copy-number analysis, and mutational signatures on HPC—with rigorous epidemiologic methods like causal mediation, polygenic risk scoring, and epigenome-wide analyses. Her work has characterized genetic and epigenetic risk factors in childhood ALL and Hodgkin’s lymphoma and even revealed accelerated epigenetic aging in Down syndrome newborns. Trained also at Columbia (MPH) and in pharmacy, she brings multidisciplinary perspective and practical teaching experience, making complex genomic findings accessible to clinical and research teams. Notably, she translates large-scale sequencing (10+ TB) into actionable insights, pairing statistical rigor with reproducible bioinformatics engineering.
code8 years of coding experience
job3 years of employment as a software developer
bookDoctor of Philosophy - PhD Epidemiology, Doctor of Philosophy - PhD Epidemiology at University of Southern California
bookMaster of Public Health - MPH Epidemiology, Master of Public Health - MPH Epidemiology at Columbia University
bookBachelor of Science - BS Pharmaceutical Sciences, Bachelor of Science - BS Pharmaceutical Sciences at East China University of Science and Technology
languagesEnglish, Chinese, wu
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Github Skills (34)

hugo-theme8
camp7
hugo7
bioinformatics5
css5
adapter4
sequencing4
python4
fasta4
bioconda4
sequence4
science4
gwas3
visual-studio-code-extension3
numerical3

Programming languages (7)

TypeScriptJuliaShellRCSSHTMLPython

Github contributions (5)

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XUKEREN/KERENXU

Mar 2018 - Aug 2022

Contributions:323 pushes, 1 branch, 2 comments in 4 years 6 months
XUKEREN/vcfannotatoR

Dec 2021 - Nov 2022

Contributions:37 commits, 35 pushes, 1 branch in 11 months
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Keren Xu - Senior Bioinformatics Scientist