Kuan-hao Chao is a Senior Deep Learning Engineer at Illumina AI Lab with nine years of experience bridging deep learning and genomics, holding a Ph.D. in Computer Science from Johns Hopkins University. His work spans sequence-to-function modeling, DNA language models, splice-site prediction with dilated residual CNNs, and producing the first gapless Southern Chinese Han genome assembly. He developed Shorkie, a masked-DNA language model pretrained on 165 fungal genomes and fine-tuned on high-resolution yeast TF induction RNA‑seq, and has applied SMT solvers and novel heuristics to make Wheeler graph problems tractable for pangenome indexing. An advocate of open source, he combines rigorous academic research with production-focused engineering to translate complex genomic signals into practical models and tools. Based in California, he welcomes collaborations that push the frontier of AI-driven biology.
9 years of coding experience
Australian National University
Bachelor of Engineering - BE, Electrical and Electronics Engineering, Bachelor of Engineering - BE, Electrical and Electronics Engineering at National Taiwan University
Johns Hopkins University
High School Diploma - Math and Science Honor, High School Diploma - Math and Science Honor at Taipei Municipal Jianguo High School
Contributions:612 commits, 2 PRs, 604 pushes in 3 years
bioinformaticssangersanger-sequencingsequencing
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Kuan-hao Chao - Senior Deep Learning Engineer at Illumina