Kuan-hao Chao

Senior Deep Learning Engineer at Illumina

California, United States
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Summary

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Rockstar
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Kuan-hao Chao is a Senior Deep Learning Engineer at Illumina AI Lab with nine years of experience bridging deep learning and genomics, holding a Ph.D. in Computer Science from Johns Hopkins University. His work spans sequence-to-function modeling, DNA language models, splice-site prediction with dilated residual CNNs, and producing the first gapless Southern Chinese Han genome assembly. He developed Shorkie, a masked-DNA language model pretrained on 165 fungal genomes and fine-tuned on high-resolution yeast TF induction RNA‑seq, and has applied SMT solvers and novel heuristics to make Wheeler graph problems tractable for pangenome indexing. An advocate of open source, he combines rigorous academic research with production-focused engineering to translate complex genomic signals into practical models and tools. Based in California, he welcomes collaborations that push the frontier of AI-driven biology.
code9 years of coding experience
bookAustralian National University
bookBachelor of Engineering - BE, Electrical and Electronics Engineering, Bachelor of Engineering - BE, Electrical and Electronics Engineering at National Taiwan University
bookJohns Hopkins University
bookHigh School Diploma - Math and Science Honor, High School Diploma - Math and Science Honor at Taipei Municipal Jianguo High School
languagesEnglish, taiwanese mandarin
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Github Skills (22)

r-package10
package-management10
seq10
conda10
sequencing10
rna-seq10
bioinformatics10
bioconda10
genome-annotation9
bioconductor7
prediction6
prediction-model6
agent-based-modeling5
simulation4
simulation-framework4

Programming languages (7)

ShellRC++JavaScriptHTMLJupyter NotebookPython

Github contributions (5)

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Kuanhao-Chao/Kuanhao-Chao

Jul 2020 - Mar 2025

Contributions:31 pushes, 1 branch in 4 years 9 months
roblanf/sangeranalyseR

Sep 2019 - Oct 2022

functions to analyse sanger sequencing reads in R
Contributions:612 commits, 2 PRs, 604 pushes in 3 years
bioinformaticssangersanger-sequencingsequencing
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Kuan-hao Chao - Senior Deep Learning Engineer at Illumina