Leo Zhang
Sr. Scientist, Cancer Vaccines & Bioinformatics Research
Greater Boston United States
Summary
👤
Senior🎓
Top SchoolLeo Zhang is a senior scientist specializing in cancer vaccines and bioinformatics, with nine years of experience building high-performance tools for genomic and multi-omics analysis. He designs and ships production-grade pipelines for individualized neoantigen therapies and metagenomics services, and authored HISAT-3N, a sequence aligner noted for being an order of magnitude faster and more accurate for nucleotide-conversion technologies. His work spans algorithm development, pipeline engineering (Nextflow), and practical integration of somatic mutation, proteogenomics, HLA typing, and MHC binding prediction to prioritize neoantigens at scale. Based in Greater Boston, he combines deep academic training (PhD in Bioinformatics) with industry impact at Moderna and a track record of enabling translational cancer research. A less obvious strength is his consistent focus on performance and reproducibility—delivering tools that accelerate both research and clinical workflows.
9 years of coding experience
6 years of employment as a software developer
Bachelor of Science (BS), Biology, Bachelor of Science (BS), Biology at Colorado State UniversityDoctor of Philosophy - PhD, Bioinformatics, Doctor of Philosophy - PhD, Bioinformatics at UT Southwestern Medical CenterOther; HMX Fundamentals online certificate program - Immunology, Other; HMX Fundamentals online certificate program - Immunology at Harvard Medical School
Github Skills (16)
graph10
hierarchical10
fm-index10
classifier3
fastq2
filemaker2
throughput1
rna-seq1
biology1
machine-learning1
genomics1
nlp1
rapid1
in-memory1
bioinformatics1
Programming languages (2)
Github contributions (5)
chbe-helix/Seqmap
Jun 2019 - Oct 2019
High-throughput gene to knowledge mapping through massive integration of public sequencing data.
Contributions:9 pushes, 1 branch in 3 months
knowledgesequencing-databiologysequencinggenomics
DaehwanKimLab/Hisat-TLA
Oct 2019 - Jan 2020
Contributions:5 pushes, 4 branches in 3 months
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