Luca Pinello
Boston, Massachusetts, United States
Summary
🤩
Rockstar🎓
Top SchoolLuca Pinello is a computational biologist and associate professor at MGH/Harvard who blends machine learning, single-cell genomics, CRISPR genome editing, and generative AI to tackle gene regulation and disease. He leads a lab that produces widely used open-source tools (CRISPResso2, CRISPRme, PrimeDesign, BEAN) and novel methods for single-cell trajectory and multimodal analysis (STREAM, Dictys, SIMBA), and his work has informed regulatory discussions around CRISPR therapies. As an associate member of the Broad Institute’s Gene Regulatory Observatory and an affiliate of the Kempner Institute, he directs large-scale functional genomics efforts within the NIH IGVF Consortium, applying base editing to dissect variant effects in heart and blood disease. His recent research extends to DNA-Diffusion, a diffusion-model approach for designing cell-type-specific regulatory sequences with therapeutic potential, reflecting a rare combination of rigorous mathematics, software engineering, and experimental collaboration. Based in Boston with 14 years of experience, he also co-founded Edilytics and trains the next generation as course co-director in computational biology at Harvard.
14 years of coding experience
7 years of employment as a software developer
Ph.D., Mathematics and Computer Science, Ph.D., Mathematics and Computer Science at Università degli Studi di Palermo
English, Italian
Stackoverflow
11reputation
414reached
0answers
1question
Github Skills (158)
plotly-dash10
package-management10
charting10
generative10
no-javascript10
gene-expression10
terminate10
genomics10
flask10
artisan10
transcription10
rna-seq10
bioconda10
plotly10
genome10
Programming languages (10)
Github contributions (5)
pinellolab/DrugThatGene
Dec 2017 - May 2020
Contributions:12 commits, 2 pushes, 3 comments in 2 years 4 months
lucapinello/CRISPResso
Feb 2015 - May 2019
Software pipeline for the analysis of CRISPR-Cas9 genome editing outcomes from sequencing data
Contributions:261 commits, 11 PRs, 347 pushes in 4 years 4 months
crispr-cas9crisprgenomepipelinesequencing-data
Find and Hire Top DevelopersWe’ve analyzed the programming source code of over 60 million software developers on GitHub and scored them by 50,000 skills. Sign-up on Prog,AI to search for software developers.