Lucas Ferreira da Silva

Boston-USA , Brazil
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Summary

👤
Senior
Lucas Da Silva is an Associate Postdoc Researcher and bioinformatician based in Boston with 11 years of experience applying generative and deep learning models to single-cell, epigenetics, and large-scale CRISPR assays. At Harvard, he explores diffusion models, CLIP, VAEs, GANs, transformers, and CNNs to decode regulatory interactions and hierarchical dependencies in genomic data. He combines a PhD in Bioinformatics from Universidade de São Paulo with hands-on postdoctoral work to design regulatory switches like promoters and enhancers using generative design approaches. Lucas favors a learning-by-creating ethos, extracting interpretable signals across disparate models and experimental modalities to explain complex biology. He has a track record of translating cutting-edge ML architectures into experimentally relevant hypotheses for Perturb-Seq and related single-cell technologies.
code11 years of coding experience
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Github Skills (70)

diffusion-models10
genomics10
text-to-image10
diffusion-probabilistic-models10
stable-diffusion10
generative-model10
dna-sequences10
deep-learning9
backend9
proot9
batch8
ai8
python8
emulation8
grid8

Programming languages (8)

RCTeXJavaScriptJupyter NotebookCommon Workflow LanguageWDLPython

Github contributions (5)

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Contributions:4 PRs, 68 pushes, 1 branch in 1 year 6 months
pinellolab/CRISPR_Pipeline

Jan 2025 - Jun 2026

Contributions:20 PRs, 79 pushes, 4 branches in 1 year 4 months
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