Lyndal Henden
Postdoctoral Researcher at Macquarie University
Sydney, New South Wales, Australia
Summary
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Senior🎓
Top SchoolLyndal Henden is a quantitative geneticist and postdoctoral researcher with a decade of experience developing statistical methods and software for relatedness analysis in human and pathogen genomes. She created and released two R packages (XIBD and isoRelate) used to detect shared ancestry and analyze complex infections, and has applied these tools to large datasets including >2,500 Plasmodium falciparum isolates across Africa, Southeast Asia and Oceania. Her PhD work produced the first algorithm for detecting X‑chromosome shared ancestry, which she has used to refine disease-critical regions in neurological disorder cohorts and uncover hidden relatedness. Now at Macquarie University’s Blair Lab she investigates genetic drivers of motor neuron disease progression with the aim of identifying targets to slow decline. Comfortable with SNP-array and NGS pipelines, she combines rigorous simulation studies with open-source software release, bringing reproducible computational practice to applied disease genomics.
10 years of coding experience
Bachelor of Science Honours (BSc. Hons), Statistics, First Class Honours, Bachelor of Science Honours (BSc. Hons), Statistics, First Class Honours at Massey UniversityThe University of Melbourne
Github Skills (3)
pairwise8
bioinformatics7
identity5
Programming languages (1)
Github contributions (3)
bahlolab/isoRelate
Nov 2016 - Mar 2018
Performs pairwise identity by descent analysis on haploid recombining organisms in the presence of multiclonal infections using SNP genotype data
Contributions:1 release, 29 commits, 1 PR in 1 year 4 months
identity-by-descentpairwisedescentgenotypebioinformatics
bahlolab/XIBD
Jul 2016 - Jul 2017
Contributions:22 commits, 25 pushes, 1 branch in 11 months
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