Madeline Couse
Senior Bioinformatician
Old Toronto, Ontario, Canada
Summary
👤
Senior🎓
Top SchoolMadeline Couse is a Senior Bioinformatician with over 11 years in genomics and 7+ years focused on whole genome analysis and clinical variant interpretation. She designs and implements NGS pipelines and production-grade applications, translating complex genomic data into actionable clinical reports for multidisciplinary teams. At institutions like The Hospital for Sick Children and UBC she led end-to-end pipeline development for diagnostic and research sequencing projects, including a $1.3M study on atypical cerebral palsy. Skilled at communicating genomic findings to clinicians and counselors, she couples rigorous data quality assessment with practical workflows that support certified reporting. Her background includes building clinician-facing web tools and exploring statistical methods for large aggregate sequencing datasets, reflecting a balance of software engineering and analytical innovation. Based in Toronto, she brings scientific depth from an MS in Genome Sciences and a track record of turning complex genomic requirements into auditable, production-ready solutions.
11 years of coding experience
4 years of employment as a software developer
Master of Science - MS, Genome Sciences/Genomics, Master of Science - MS, Genome Sciences/Genomics at The University of British ColumbiaBachelor of Science - BS, Honours Biology, Bachelor of Science - BS, Honours Biology at University of Waterloo
Github Skills (42)
genomics10
nextflow9
pipeline9
bioinformatics9
structural-variation8
genetics8
simulator7
expressions7
genetic7
sequence7
bioconda6
excel6
sequencing6
ranking6
simulation6
Programming languages (13)
Github contributions (5)
ccmbioinfo/cre
May 2020 - Nov 2022
excel report generation using data from bcbio variant2 germline pipeline
Contributions:10 reviews, 114 commits, 53 PRs in 2 years 7 months
excel
ccmbioinfo/crg2
May 2020 - Jan 2023
Research pipeline for exploring clinically relevant genomic variants
Contributions:62 reviews, 346 commits, 168 PRs in 2 years 8 months
pipelinegenomicsnextflowbioinformaticsgenomic
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