Mahesh Nepal
Research Scientist at BioCryst Pharmaceuticals, Inc.
Birmingham, Alabama, United States
Summary
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Senior🎓
Top SchoolMahesh Nepal is a research scientist with over a decade of hands-on experience in early-phase clinical pharmacology, preclinical PK/ADME, and drug transporter biology, now applying that expertise at BioCryst Pharmaceuticals. He has authored 20+ peer-reviewed publications dissecting transporter-mediated drug uptake and toxicity mechanisms, particularly for anticancer agents and statins, and routinely combines in vitro, in vivo, and LC-MS/MS approaches to translate mechanistic findings into biomarker strategies. His work uniquely emphasizes identification of endogenous transporter substrates as potential functional biomarkers, bridging molecular pharmacology with clinically relevant safety and DDI risk assessment. Trained to PhD level and experienced across academic and industry settings, he also brings practical QA and method-development skills from earlier pharmaceutical roles. Based in Birmingham, AL, he is driven to advance collaborative, translational research that reduces toxicity without compromising therapeutic benefit.
10 years of coding experience
8 years of employment as a software developer
Bachelor's degree, Pharmacy, Bachelor's degree, Pharmacy at Kathmandu University (KU)Kathmandu University, Bachelor of Pharmacy, Kathmandu University, Bachelor of Pharmacy at Bagmati Higher Secondary SchoolBagmati Boarding SchoolDoctor of Philosophy - PhD, Pharmacy, Doctor of Philosophy - PhD, Pharmacy at Yeungnam University
English, Nepali, Hindi, Korean
Stackoverflow
1,431reputation
1.0mreached
18answers
7questions
typescript
top-5%
Github Skills (11)
typescript9
json6
trackbar6
elasticsearch6
netcore6
vector6
nest6
angular6
relational-databases3
react2
crowdsourcing1
Programming languages (3)
Github contributions (5)
manepal/Sqorm
Feb 2020 - Feb 2020
Lightweight Object-Relational Mapper for relational databases
Contributions:1 release, 22 commits, 27 pushes in 8 days
relational-databases
ojastechnologies/ojas-web
Feb 2026 - Jun 2026
This is an official web site repo of Ojas Technologies
Contributions:2 PRs, 25 pushes in 3 months
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