Malachi Griffith
Professor Of Medicine at Canadian Bioinformatics Workshops
St. Louis, Missouri, United States
Summary
🤩
Rockstar🎓
Top SchoolMalachi Griffith is a Professor of Medicine and co-leader of the Griffith Lab at Washington University with 13+ years of experience applying molecular biology, bioinformatics, and biostatistics to translational cancer research. He directs genome-scale projects at the McDonnell Genome Institute, developing methods for RNA-seq, whole-genome sequencing, mutation discovery and clinical genomics integration. His work bridges wet-lab and computational domains—ranging from tissue culture and Sanger validation to Perl/R pipelines, mySQL-backed databases, and C/C++ tools—enabling clinically actionable insights in cancer genomics and immunogenomics. An experienced educator and technical writer, he has produced widely used RNA-seq tutorials and taught advanced sequencing courses at Cold Spring Harbor and international workshops. Notably, he and his twin brother jointly lead a lab that emphasizes generalizable and personalized cancer therapies, reflecting a rare combination of collaborative leadership and hands-on method development. Based in St. Louis, he pairs deep academic training (PhD in medical genetics/bioinformatics) with a sustained record of translating genomic discovery into clinical and educational resources.
14 years of coding experience
12 years of employment as a software developer
BA, Business Computing, BA, Business Computing at The University of WinnipegHonors project, Molecular Biology, Honors project, Molecular Biology at University of ManitobaPhD, Medical Genetics, Bioinformatics, Genomics, PhD, Medical Genetics, Bioinformatics, Genomics at The University of British ColumbiaPhD, Molecular Biology and Biochemistry, PhD, Molecular Biology and Biochemistry at Simon Fraser University
English
Github Skills (4)
documentation10
r10
rna-seq9
bioinformatics9
Programming languages (20)
Github contributions (5)
griffithlab/rnaseq_tutorial
Jul 2014 - Jun 2020
Informatics for RNA-seq: A web resource for analysis on the cloud. Educational tutorials and working pipelines for RNA-seq analysis including an introduction to: cloud computing, critical file formats, reference genomes, gene annotation, expression, differential expression, alternative splicing, data visualization, and interpretation.
Role in this project:
Technical Writer
Technical WriterContributions:191 commits, 2 PRs, 168 pushes in 5 years 11 months
Contributions summary:Malachi's contributions primarily involve modifications to documentation and tutorial files within the repository. They focused on adding comments, reformatting existing code, and updating emails and affiliations. The changes also included adding and formatting axis labels and modifying output file headers, suggesting a focus on clarity and user-friendliness within the tutorial.
cloud-computingdata-visualizationrna-seq
wustl-oncology/immuno_gcp_wdl_compute1
Feb 2022 - Nov 2025
Tutorial for running immuno.wdl on Google Cloud starting from local data
Contributions:1 release, 4 reviews, 4 PRs in 3 years 9 months
google-cloud
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