Manu Setty
Assistant Professor at Fred Hutch
Seattle, Washington, United States
Summary
👤
Senior🎓
Top SchoolManu Setty is an Assistant Professor and computational biologist with 12 years of experience modeling and integrating high-throughput genomics data, currently leading translational data science efforts at Fred Hutch in Seattle. He develops machine learning methods for representation and visualization of single-cell RNA-seq and performs integrative analyses across RNA-, DNase-, ATAC-, histone, and TF ChIP-seq datasets. His work bridges computational method development and experimental collaboration, evidenced by first-author papers in Nature Biotechnology, Nature Genetics, Nature MSB and PLoS Computational Biology. With a PhD in Bioinformatics and prior roles at Memorial Sloan Kettering, Columbia and industry at Celsius Therapeutics, he combines academic rigor with applied biotech experience. Notably, his research trajectory emphasizes creating interpretable representations that facilitate biological discovery rather than black-box prediction.
12 years of coding experience
3 years of employment as a software developer
PhD, Bioinformatics, Systems Biology, Machine Learning, PhD, Bioinformatics, Systems Biology, Machine Learning at Weill Cornell Medical CollegeMS, Computer Science - Computational Biology, MS, Computer Science - Computational Biology at Columbia EngineeringBachelor of Engineering, Computer Science, Bachelor of Engineering, Computer Science at National Institute of Technology Karnataka
Kannada
Github Skills (42)
crossword10
single-cell-genomics10
markov-chain10
dimensionality-reduction10
trajectory-generation10
seq10
imputation10
affinity10
differentiation10
topological-data-analysis10
single-cell-analysis10
wolfram-language10
markov10
points10
harmony9
Programming languages (4)
Github contributions (5)
ManuSetty/SeqGL
Jan 2014 - Mar 2021
SeqGL is a group lasso based algorithm to extract TF sequence signals from ChIP, DNase and ATAC-seq profiles
Contributions:1 release, 10 commits, 1 PR in 7 years 3 months
sequencechipataclassogroup-lasso
settylab/Palantir
Jan 2022 - Jun 2023
Single cell trajectory detection
Contributions:2 reviews, 3 PRs, 3 pushes in 1 year 5 months
deep-learningsingle-celltrajectory
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