Marco Di Stefano
CNRS Researcher (CR) at Institut de Génétique Humaine
Montpellier, Occitania, France
Summary
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Senior🎓
Top SchoolMarco Di Stefano is a CNRS researcher specializing in 3D genome organization, combining polymer physics, molecular dynamics and data-driven modeling to reveal how chromatin folding influences gene regulation. With a PhD from SISSA and nine years of postdoctoral and research experience at CNAG-CRG and IGH, he has led studies on transcription dynamics during cell reprogramming and on epigenomics–folding interplay in plants and mammals. He bridges computational modeling and high-level bioinformatics, translating Hi-C and other chromatin interaction data into high-resolution chromosome models and mechanistic insights. Marco co-founded the citizen-science Genigma project to bring 3D genomics tools to cancer variant detection, highlighting his interest in public engagement and translational impact. He is known for developing hybrid experimental-computational approaches and for an early record of producing whole-chromosome models from co-expression and contact data. Based in Montpellier, he combines rigorous physics training with practical bioinformatics to tackle complex questions in genome architecture.
9 years of coding experience
9 years of employment as a software developer
Diploma, Liceo Classico, 100/100, Diploma, Liceo Classico, 100/100 at Liceo Classico L.A. SenecaDoctor of Philosophy (PhD), Physics and Chemistry of Biological Systems, Doctor of Philosophy (PhD), Physics and Chemistry of Biological Systems at Scuola Internazionale Superiore di Studi Avanzati di TriestePost-doctoral training in Chromosome structure determination using modelling and Hi-C data, Biomathematics, Bioinformatics, and Computational Biology, Post-doctoral training in Chromosome structure determination using modelling and Hi-C data, Biomathematics, Bioinformatics, and Computational Biology at Instituto Gulbenkian de CienciaMaster's degree, Physics - Curriculum Biophysics, 110/110 cum laude, Master's degree, Physics - Curriculum Biophysics, 110/110 cum laude at Sapienza Università di Roma
Italian, English, Spanish
Github Skills (29)
fastq-files10
fastq9
explore9
3d-models9
interaction9
python8
genomics6
bioinformatics6
sparse6
file-format6
genome5
hierarchical4
python-bindings4
computational-biology3
rna-seq3
Programming languages (6)
Github contributions (5)
MarcoDiS/Athaliana_simulations
Dec 2020 - Jan 2024
Contributions:4 pushes in 3 years 1 month
MarcoDiS/TADbit
Jul 2016 - May 2017
Contributions:9 pushes, 1 branch in 10 months
pythondealstepshi-cdomains
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