Marius Lange
Postdoctoral Researcher at ETH Zürich
Basel, Basel-City, Switzerland
Summary
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Senior🎓
Top SchoolMarius Lange is an applied mathematician and postdoctoral researcher with nine years of experience at the interface of machine learning and single-cell genomics, currently working at ETH Zürich after a summa cum laude PhD from TUM/Helmholtz Munich. He develops computational frameworks—most notably CellRank—for studying cell fate decisions by integrating gene expression, RNA velocity, lineage tracing and spatial multi-omics. His work blends theory (optimal transport, dynamical systems) with practical tooling applied to development, regeneration and organoid disease models, bridging academic rigor and broadly useful open-source software. A proven international collaborator with visiting stints at MSKCC and Hebrew University, he combines physics-trained quantitative intuition with biological curiosity to turn complex single-cell assays into interpretable dynamical models.
9 years of coding experience
5 years of employment as a software developer
Abitur (High school), 1.0, Abitur (High school), 1.0 at Droste-Hülshoff-Gymnasium FreiburgErasmus exchange, Physics, Erasmus exchange, Physics at Imperial College LondonMaster of Science - MS, Computational and Applied Mathematics, Distinction, Master of Science - MS, Computational and Applied Mathematics, Distinction at University of OxfordDoctor of Philosophy - PhD, Computational Biology, Summa cum laude, Doctor of Philosophy - PhD, Computational Biology, Summa cum laude at Technical University of MunichLiberal Arts and Sciences/Liberal Studies, Liberal Arts and Sciences/Liberal Studies at The University of FreiburgExchange Student in High School, Exchange Student in High School at Bainbridge High School
German, English, French, Spanish
Github Skills (86)
python10
spatial-transcriptomics10
transcriptomics10
single-cell-analysis10
data-science10
rna-velocity10
scanpy10
genetics10
single-cell-genomics10
hierarchical10
trajectory-generation10
machine-learning10
segmentation10
bioinformatics10
representation-learning9
Programming languages (6)
Github contributions (5)
theislab/cellrank_reproducibility_preprint
Oct 2020 - Jan 2022
Code to reproduce results from the CellRank preprint
Contributions:71 commits, 4 PRs, 7 pushes in 1 year 3 months
bioinformaticscellrankmanuscriptreproducefate
quadbio/cellmapper
Apr 2025 - Jun 2026
k-NN-based mapping of cells across representations to transfer labels, embeddings, and expression values.
Contributions:6 releases, 44 PRs, 138 pushes in 1 year 1 month
knndata-integrationgenomicsk-nnrepresentation-learning
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