Martin Steinegger

Associate Professor

Seoul Incheon Metropolitan Area South Korea
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Summary

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Martin Steinegger is an associate professor and computational biologist with 14 years of experience building high-performance algorithms for sequence search, clustering, and metagenome analysis. He leads method development that combines big-data algorithms and machine learning to mine microbial diversity, and his lab produced widely used tools such as MMseqs2 and Foldseek that dramatically accelerate homology and structure searches. A hands-on back-end developer and build engineer, he regularly contributes performance and correctness fixes across major open-source projects (MMseqs2, HH-suite, Kraken2, ColabFold) and improves reproducible packaging via bioconda. His background spans academia and industry—from scalable cloud/HPC implementations at the Max Planck Söding Lab to production-facing pipelines—giving him an uncommon blend of deep algorithmic insight and pragmatic software engineering.
code14 years of coding experience
job13 years of employment as a software developer
bookDoctor of Philosophy (PhD), Computer Science, Doctor of Philosophy (PhD), Computer Science at Technical University Munich
bookLudwig Maximilian University of Munich
bookBachelor of Science (B.Sc.), Bioinformatics, passed with merit, Bachelor of Science (B.Sc.), Bioinformatics, passed with merit at Technische Universität München
bookComputer Engineering, Computer Engineering at HTL Braunau
bookBusiness Informatics, Software Engineering, Business Informatics, Software Engineering at Edvschule Plattling
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1,121reputation
70kreached
5answers
26questions
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Github Skills (37)

algorithm10
debugging10
algorithms10
debug10
c-language10
python10
package-management10
scripting10
conda10
cmake10
data-structure10
script10
performance-optimization10
bioinformatics10
sh10

Programming languages (9)

ShellC++CJavaScriptVueHTMLJupyter NotebookRuby

Github contributions (5)

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steineggerlab/foldseek

Sep 2018 - Jan 2023

Foldseek enables fast and sensitive comparisons of large structure sets.
Role in this project:
userBack-end Developer
Contributions:5 releases, 2 reviews, 346 commits in 4 years 4 months
Contributions summary:Martin appears to have been actively involved in the development and maintenance of the Foldseek project's core code. Their commits focus on modifying and enhancing existing algorithms like TM-align and NN-based alignment. The user also made efforts to optimize the code for performance and added support for features.
protein-structurealignmentssensitivecomparisonsbioinformatics
soedinglab/MMseqs2

Mar 2013 - Dec 2022

MMseqs2: ultra fast and sensitive search and clustering suite
Role in this project:
userBack-end Developer
Contributions:26 releases, 6 reviews, 1982 commits in 9 years 10 months
Contributions summary:Martin contributed primarily to the MMseqs2 codebase through bug fixes and improvements to existing functionality. Their commits focused on addressing data type inconsistencies, integrating a touch function within the prefiltering module, and correcting coordinate calculations within the alignment process. Moreover, they were also involved in merging changes from the master branch. Their work involved changes to various source files like QueryMatcher.cpp, QueryMatcher.h and also contributions to the core algorithm in src/alignment.
profile-searchmetagenomicsalignmentultrammseqs
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