Matteo Degiacomi

Reader at The University of Edinburgh

England, United Kingdom
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Summary

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Matteo Degiacomi is a computational biophysicist and Reader at the University of Edinburgh with 11 years of experience developing methods for molecular modelling, integrative structural biology, and mass spectrometry data analysis. He bridges computer science and biotechnology, applying machine learning and optimization to molecular simulation, protein assembly, and interpretive mass-spec problems. Previously he led a research group at Durham University and built open tools (e.g., the POW optimization environment) during roles at EPFL and Oxford, demonstrating a commitment to open-source method development. His work uniquely combines rigorous algorithm development with hands-on biophysical modeling, enabling insights into complex assemblies rather than just tool-building. Trained at EPFL with a PhD in Biotechnology and a Master’s in Computer Science, he frequently collaborates across informatics and chemistry boundaries. Colleagues describe him as a method-focused scientist who turns challenging experimental data into predictive models.
code11 years of coding experience
job12 years of employment as a software developer
bookDoctor of Philosophy (Ph.D.), Biotechnology, Doctor of Philosophy (Ph.D.), Biotechnology at Ecole polytechnique fédérale de Lausanne
languagesItalian, French, English, German
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Github Skills (32)

forge10
structural-biology9
toolbox9
dynamics9
bioinformatics9
protein-structure9
computational-biology9
descriptor9
conda8
machine-learning8
manipulation8
docking8
simulation8
journal7
conda-forge7

Programming languages (2)

Jupyter NotebookPython

Github contributions (5)

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degiacom/assemble

Feb 2015 - Feb 2019

a tool for creating Molecular Dynamics-ready models of polymeric systems
Contributions:29 commits, 7 PRs, 19 pushes in 4 years 1 month
pythonmolecular-dynamicssimulationmoleculardynamics
Degiacomi-Lab/biobox

Jan 2017 - May 2022

a toolbox for the manipulation, modelling and analysis of molecular structures
Contributions:1 release, 76 commits, 1 PR in 5 years 5 months
manipulationpythontoolboxmolecular-structuresstructural-biology
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Matteo Degiacomi - Reader at The University of Edinburgh