Summary
Matthew Tien is a senior scientist and microbial engineer with 13 years of experience designing genetic and molecular tools to scale industrial biotechnology, bioremediation, and green chemistry. He holds a PhD from the University of Chicago and honed post-transcriptional regulation expertise as a postdoc at MIT, where he engineered strains with tunable endo- and exonuclease activity and developed end-enriched RNA-seq approaches. As an assistant professor he led a lab combining sequence-to-expression CNN models, high-throughput screens, and genetic manipulation of natural isolates to translate fundamental RNA biology into practical bioprocesses. He is proficient in Python and R, authored a widely used PeptideBuilder.py earlier in his career, and blends computational network analysis with hands-on biochemical purification methods. Based in Austin, Matthew aims to deploy engineered microbes and cell-free systems for sustainable, industry-scale solutions to environmental challenges.
13 years of coding experience
9 years of employment as a software developer
Bachelor of Science - BS, Biochemistry, Dean's Honored Graduate, Bachelor of Science - BS, Biochemistry, Dean's Honored Graduate at The University of Texas at Austin
Doctor of Philosophy - PhD, Biochemistry and Molecular Biology, Doctor of Philosophy - PhD, Biochemistry and Molecular Biology at University of Chicago