Matthieu Muffato
Informatics Infrastructure Team Lead
Cambridge, England, United Kingdom
Summary
🤩
Rockstar🎓
Top SchoolMatthieu Muffato is an informatics infrastructure leader with 41 years of experience building and running large-scale genomics workflows, currently heading the Tree of Life programme’s Informatics Infrastructure team at the Wellcome Sanger Institute. He combines deep domain expertise in comparative genomics, phylogenetics and workflow management (notably eHive and Ensembl Compara) with hands-on software engineering across Perl, Python and cloud/cluster systems. Matthieu has stewarded major compute and data strategy revamps to enable comparative analyses at unprecedented scale—tens of thousands of genomes—and acts as the bridge between research teams and IT. He is an active open-source contributor to the nf-core ecosystem, adding and improving Nextflow modules for core bioinformatics tools. Colleagues describe him as both a practical implementer and a mentor who transfers institutional knowledge while modernizing pipelines. His background in reconstructing ancestral genomes during his PhD gives him a rare combination of theoretical insight and production-grade engineering.
41 years of coding experience
10 years of employment as a software developer
Master's degree, Bioinformatics, Master's degree, Bioinformatics at Université d'Evry-Val d'EssonneEngineer's degree, Computer science, eq. MSc, Engineer's degree, Computer science, eq. MSc at ENSIIEMathematics, Physics, Mathematics, Physics at Lycée Louis-le-GrandBachelor of Science - BS, Mathematics, Bachelor of Science - BS, Mathematics at Université Paris Diderot
French, English, Spanish, Korean
Github Skills (19)
go-modules10
dsl10
work-flow10
workflow-engine10
kernel-module10
nextflow10
workflow-automation10
pipeline10
bioinformatics10
jsmodules10
dockers9
containerization9
docker9
shell8
sh8
Programming languages (24)
Github contributions (5)
nf-core/modules
Feb 2022 - Jan 2023
Repository to host tool-specific module files for the Nextflow DSL2 community!
Role in this project:
Back-end Developer
Back-end DeveloperContributions:242 reviews, 31 commits, 129 PRs in 11 months
Contributions summary:Matthieu contributed significantly to the nf-core/modules repository, primarily by developing and modifying modules for various bioinformatics tools. Their work involved creating new modules for tools like `biobambam/bammarkduplicates2`, `samtools/dict`, `fasta_windows`, and `miniprot`, alongside updates to existing modules such as `bwamem2`, `samtools`, `ucsc`, and `tabix`. The contributions included adding support for features like `ext.args`, meta maps, and newer container versions.
nextflownf-coreworkflowspipelinesdsl2
muffato/ensembl-webcode
Jan 2015 - Dec 2020
My fork of Ensembl/ensembl-webcode. Only used to submit pull-requests
Contributions:20 pushes, 73 branches in 6 years
ensemblpull-requestssubmit
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