Summary
Michael Breen is an Associate Professor of Genetics & Genomics in Psychiatry at Icahn School of Medicine with nine years of focused experience translating multi-omic data into mechanistic insights for brain development and rare neurodevelopmental disorders. He leads integrative studies of A-to-I RNA editing, mRNA and proteomic dynamics, and develops oligonucleotide-directed RNA editing therapeutics using patient-derived hiPSC-neuronal models. His work combines rigorous computational method development, large-scale consortium collaborations (e.g., CommonMind, AMP-AD, Autism Sequencing Consortium), and hands-on molecular tool design to move targets from discovery toward therapeutic repair. He manages multi-million-dollar research programs while mentoring teams to uphold reproducible, high-quality science. Hidden strength: he bridges deep statistical and machine-learning expertise with wet-lab RNA-editing innovation, enabling both biomarker discovery and novel corrective therapies.
9 years of coding experience
13 years of employment as a software developer
Doctor of Philosophy (Ph.D.), Bioinformatics and Genomics, Doctor of Philosophy (Ph.D.), Bioinformatics and Genomics at University of Southampton
english, spanish and novice bulgarian