Michael Clerx

Senior Research Fellow at University of Nottingham

Greater Oxford Area United Kingdom
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Summary

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Senior
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Michael Clerx is a Senior Research Fellow based in the Greater Oxford Area with a decade of experience applying mathematical modelling and numerical techniques to cardiac electrophysiology. He investigates how subtle ion channel changes and mutations drive life-threatening arrhythmias by linking single-cell channel behavior to tissue-level dysfunction using computational models. Holding a PhD in Computational Cardiac Cellular Electrophysiology and an MSc in Artificial Intelligence, he blends biophysics, machine learning concepts, and rigorous simulation to probe mechanisms that are difficult to access experimentally. His work sits at the intersection of theory and translational impact, informing both basic science and potential therapeutic strategies. An unexpected strength is his background in mechanical engineering and applied physics, which gives him a practical, cross-disciplinary perspective on model development and numerical implementation.
code10 years of coding experience
bookPhD, Computational Cardiac Cellular Electrophysiology, PhD, Computational Cardiac Cellular Electrophysiology at Maastricht University
bookMechanical Engineering, Mechanical Engineering at Eindhoven University of Technology
bookBC Broekhin
languagesEnglish, Dutch
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2,988reputation
310kreached
62answers
53questions
Badges
machine-learning
top-5%
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Github Skills (200)

gradient-descent10
computational-neuroscience10
python10
numerics10
gtk10
numerical-optimization10
bayesian-methods10
computational-biology10
scientific-computing10
qt10
animation10
video-processing10
electrophysiology10
numpy10
inverse-problems10

Programming languages (19)

C#CSSJinjaC++RustTeXMakefileGo

Github contributions (5)

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Examples of parameter estimation in cardiac cell electrophysiology using Myokit and PINTS.
Contributions:13 PRs, 238 pushes, 27 branches in 6 years 6 months
cardiacdata-analysiscomputational-neuroscienceparameterestimation
myokit/datkit

Aug 2023 - Mar 2025

Silly scripts for working with time-series data
Contributions:3 releases, 5 PRs, 16 pushes in 1 year 7 months
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Michael Clerx - Senior Research Fellow at University of Nottingham