Michael Coyle
Senior Director - Translational Biology
Durham, North Carolina, United States
Summary
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Senior🎓
Top SchoolMichael Coyle is a translational biology leader with a Ph.D. in Chemistry and a decade of hands-on experience engineering proteins and bioconjugates to improve therapeutic delivery, pharmacokinetics, and biodistribution. He has advanced drug delivery from concept to clinic-readiness—optimizing XTEN-based half-life extension, designing orally dosed biologic formulations, and developing assays for multiplexed in vivo quantitation. Comfortable at the interface of chemistry, cell biology, and formulation science, he combines site-selective conjugation and rigorous analytics (MS, HPLC, light scattering) with microscopy- and PK-driven functional readouts. At Life Edit Therapeutics he progressed from protein chemistry lead to Senior Director, reflecting a track record of technical leadership and cross-functional translation. Colleagues value his ability to turn complex biophysical problems into practical development strategies, and he brings uncommon expertise in both enteric solid-dosage formulation and live-cell receptor organization assays.
10 years of coding experience
11 years of employment as a software developer
Ph.D. Chemistry, Ph.D. Chemistry at University of California, BerkeleyBachelor of Arts (B.A.) Biochemistry and Molecular Biology, Bachelor of Arts (B.A.) Biochemistry and Molecular Biology at Boston University
Github Skills (2)
discovery8
pipeline5
Programming languages (1)
Github contributions (5)
CRISPRlab/CRISPRdisco
Dec 2017 - Mar 2018
CRISPR discovery pipeline
Contributions:27 commits, 26 pushes, 1 branch in 2 months
crisprpipelinediscoverydiscovery-pipelineworkflow
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