Mudra Hegde
Staff Scientist, Bioinformatics
Carlsbad, California, United States
Summary
👤
Senior🎓
Top SchoolMudra Hegde is a Staff Scientist in Bioinformatics with nine years of experience developing and maintaining analysis pipelines and tools for functional genomics screens, especially CRISPR modalities (CRISPRko/a/i and base editing). Based in Carlsbad, she combines a strong computational biology background—M.S. in Bioinformatics—with software skills honed at the Broad Institute and Thermo Fisher Scientific to design genome-wide guide libraries and optimize novel CRISPR technologies. She mentors bench scientists and early-career computational biologists, translating wet-lab needs into robust, benchmarked bioinformatics solutions and clear results for collaborators. Known for pragmatic tool-building and rigorous benchmarking against published methods, she bridges research and engineering to enable reproducible screening analyses. An early-career detail that endures in her approach: she began by detecting off-target effects in RNAi screens, a perspective that informs her careful evaluation of guide efficiency and specificity today.
9 years of coding experience
10 years of employment as a software developer
Bachelor of Engineering (B.E.), Computer Science and Engineering, Bachelor of Engineering (B.E.), Computer Science and Engineering at M.S. Ramaiah Institute of Technology, BangaloreMaster's degree, Bioinformatics, Master's degree, Bioinformatics at Northeastern University
English, Hindi, Kannada
Github Skills (9)
genes8
combinations6
bioinformatics5
genomics5
pipeline3
validation3
python2
machine-learning1
deep-learning1
Programming languages (3)
Github contributions (5)
mhegde/gen-programmed-pairs
Jul 2019 - Jun 2022
This script helps make sgRNA combinations for programmed pairs of genes.
Contributions:21 commits, 4 PRs, 15 pushes in 2 years 11 months
sgrnacombinationsgenomicsbioinformaticsgenes
mhegde/auc-calculation
Feb 2018 - May 2020
Contributions:15 commits, 12 pushes, 6 branches in 2 years 3 months
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