Muhammad Shamim

Clinical Pathology Resident

Cambridge, Massachusetts, United States
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Summary

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Senior
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Top School
Muhammad Shamim is a clinical pathology resident and MD/PhD trained physician-scientist with 11 years of experience at the intersection of genomics, bioinformatics, and clinical medicine. He brings deep technical chops from a Computer Science/Applied Math background and hands-on bioinformatics work in the Aiden Lab, where he contributed scripting and workflow automation to the widely used juicer Hi-C analysis pipeline. A Paul & Daisy Soros Fellow and former Donald A. Elliott Scholar, he combines rigorous research training from Rice and Baylor with practical DevOps and high-performance computing experience (UGER/SLURM). Based in Cambridge, MA, he has a track record of translating complex computational methods into reproducible tools for pathology and genomics.
code11 years of coding experience
job5 years of employment as a software developer
bookDoctor of Philosophy - PhD Bioengineering, Doctor of Philosophy - PhD Bioengineering at Rice University
bookMD/PhD Medical Scientist Training Program, MD/PhD Medical Scientist Training Program at Baylor College of Medicine
bookHigh School, High School at The Science Academy of South Texas
languagesEnglish, urdu/hindi, Spanish, Arabic
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Github Skills (15)

bioinformatics10
bash10
devops10
slurm9
automation9
automations9
genomics8
python8
data-pipeline8
data-pipelines8
ng7
scripting7
script7
sh7
shell7

Programming languages (14)

C#JavaC++CTeXHTMLKotlinTypeScript

Github contributions (5)

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aidenlab/juicer

Dec 2015 - Jul 2022

A One-Click System for Analyzing Loop-Resolution Hi-C Experiments
Role in this project:
userBack-end & DevOps Engineer
Contributions:1 review, 52 commits, 23 PRs in 6 years 7 months
Contributions summary:Muhammad contributed significantly to the `juicer` repository, focusing on scripting and automation tasks. They developed and updated bash scripts for managing and processing Hi-C data, specifically related to the mega-map pipeline. The contributions also involved modifying scripts for job submission and optimizing the workflow within the UGER and SLURM environments.
analyzingone-clickpipeline-framework3d-genomeresolution
Robust implementation of Concurrent KMeans to handle missing values
Contributions:4 releases, 2 PRs, 13 pushes in 1 year 2 months
missing-valuesmissingkmeanshandleconcurrent
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Muhammad Shamim - Clinical Pathology Resident