Nathan Lapierre

Research Fellow at Dana-Farber Cancer Institute

United States
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Summary

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Senior
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Top School
Nathan LaPierre is a computational biologist and postdoctoral research fellow at Harvard Medical School and Dana-Farber Cancer Institute with 11 years of experience bridging machine learning, statistical genetics, and genomics. He develops deep generative models applied to single-cell data to make causal predictions of perturbation effects, building on prior work in Mendelian randomization, fine-mapping, disease prediction with deep learning, and metagenomics. His trajectory spans impactful academic research from a PhD at UCLA through postdoctoral roles at the University of Chicago, and includes early bioinformatics contributions such as the CAMIL multiple-instance learning pipeline for microbiome-based disease prediction. Comfortable moving between software engineering and statistical methodology, he brings practical systems experience from industry internships and a history of publishing in competitive bioinformatics venues. Colleagues describe him as someone who combines theoretical rigor with hands-on model engineering to translate high-dimensional biology into testable causal hypotheses.
code11 years of coding experience
job8 years of employment as a software developer
bookAdvanced Studies Diploma, Advanced Studies Diploma at Thomas Jefferson High School for Science and Technology
bookUniversity of California, Los Angeles
bookBachelor of Science (B.S.) Computer Software Engineering, Bachelor of Science (B.S.) Computer Software Engineering at George Mason University
languagesEnglish
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Github Skills (41)

fine-mapping10
bioinformatics10
hash10
containment10
decomposition9
package-management9
conda9
profiling9
principal-component-analysis9
bioconda8
gwas8
sampling8
causal7
traits6
statistics6

Programming languages (9)

ShellRC++TeXJavaScriptHTMLJupyter NotebookRuby

Github contributions (5)

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smangul1/MiCoP

Dec 2017 - Mar 2022

MiCoP is a method for high-accuracy profiling of viral and fungal metagenomic communities.
Contributions:22 commits, 21 pushes, 17 comments in 4 years 4 months
profilingviralhigh-accuracymethodcommunities
nlapier2/Metalign

Sep 2018 - Nov 2020

Metalign: efficient alignment-based metagenomic profiling via containment min hash
Contributions:8 releases, 259 commits, 1 PR in 2 years 1 month
profilingcontainmentalignmenthash
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Nathan Lapierre - Research Fellow at Dana-Farber Cancer Institute