Nicole Ortogero
Associate Director Of Bioinformatics Software Engineering
Seattle, Washington, United States
Summary
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Senior🎓
Top SchoolNicole Ortogero is an Associate Director of Bioinformatics Software Engineering with nine years of experience building and scaling bioinformatics platforms at the intersection of biology and software. At Bruker Spatial Biology she has led teams and infrastructure since 2018, translating complex spatial-omics requirements into production-ready pipelines and tools. Her background spans hands-on sequencing method development and automation integration—she developed a novel small RNA sequencing approach during her PhD and later drove a threefold lab throughput increase through automated liquid handling. Nicole combines statistical rigor from her biostatistics work at Madigan with practical regulatory and GLP experience from Charles River, making her comfortable in both research and compliance-driven environments. She is based in the Greater Seattle Area and brings a rare blend of deep wet-lab sequencing expertise, C++/Python engineering, and leadership in deploying bioinformatics at scale.
9 years of coding experience
12 years of employment as a software developer
Doctor of Philosophy (Ph.D.), Cellular and Molecular Biology, Doctor of Philosophy (Ph.D.), Cellular and Molecular Biology at University of Nevada-Reno
Github Skills (22)
machine-learning10
normalization10
spatial10
rcc10
documentation10
sarif9
r-package9
derived9
bioconductor9
traits9
tensorflow9
deep-learning9
plugin8
deep-neural-networks8
image-processing7
Programming languages (5)
Github contributions (5)
Nanostring-Biostats/GeomxTools
Dec 2020 - Apr 2022
Tools for NanoString GeoMx Digital Spatial Profiler data for reading DCC and PKC files to NanoStringGeomxSet class, Normalization and QC.
Contributions:6 releases, 66 reviews, 265 commits in 1 year 4 months
dccnanostringspatialnormalizationdata-profiler
Nanostring-Biostats/GeoDiff
Oct 2021 - Apr 2022
GeoDiff, an R package for count generating models for analyzing Geomx RNA data. Note that this version of the package is still under development, undergoing submission process to Bioconductor 3.14 release and still needs to complete NanoString internal verification process.
Contributions:1 release, 11 reviews, 20 commits in 6 months
analyzingr-packageinternalnanostringbioconductor
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