Olga Botvinnik

Founder at Seanome

San Francisco, California, United States
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Summary

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Olga Botvinnik is a computational biologist and founder with 14 years of experience building open genomics tools that bridge single-cell transcriptomics, comparative evolution, and reproducible bioinformatics. She holds a PhD in single-cell RNA-sequencing and led cross-species “dark matter” transcriptome analyses at CZ Biohub, producing an openly available draft manuscript and tools for translating RNA reads into protein-coding sequence. Olga is an active open-source maintainer and creator—contributing to high-profile projects like nf-core, seaborn, and sourmash while authoring popular libraries such as Sencha and prettyplotlib. She blends hands-on pipeline and DevOps expertise (Nextflow, Docker, AWS) with mentorship and community outreach, from running coding clinics to a bioinformatics Twitch channel. Now based in San Francisco, she’s applying that toolkit to unlock discoveries from ocean biodiversity as founder of Seanome.
code14 years of coding experience
job11 years of employment as a software developer
bookS.B. S.B. Mathematics Biological Engineering, S.B. S.B. Mathematics Biological Engineering at Massachusetts Institute of Technology
bookUniversity of California, San Diego
bookInternational Baccalaureate Diploma, International Baccalaureate Diploma at South Eugene High School
bookUniversity of California Santa Cruz
languagesRussian, French, Japanese
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Stats
1,594reputation
184kreached
14answers
21questions
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Github Skills (32)

data-visualizations10
python10
data-science10
matplotlib10
pandas10
data-visualisation10
histogram10
astar10
nextflow10
fstar10
heatmap10
rna-seq10
bioinformatics10
data-visualization10
dstar10

Programming languages (25)

CStandard MLMakefileNextflowGoHTMLJupyter NotebookGroovy

Github contributions (5)

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olgabot/prettyplotlib

Jul 2013 - Oct 2014

Painlessly create beautiful matplotlib plots.
Role in this project:
userFull-stack Developer
Contributions:202 commits, 1 comment in 1 year 2 months
Contributions summary:Olga's contributions primarily focused on enhancing the prettyplotlib library by adding new functionalities related to plotting. They added the ability to annotate bar plots and provided new options for gridlines within histogram plots. The user was also involved in fixing layout issues, adjusting text colors, and addressing conflicts related to plotting commands.
pythonmatplotlibdata-visualizationplottingplots
nf-core/scrnaseq

Jun 2019 - Jul 2019

A single-cell RNAseq pipeline for 10X genomics data
Role in this project:
userBack-end Developer & DevOps Engineer
Contributions:2 reviews, 61 commits, 3 PRs in 1 month
Contributions summary:Olga primarily contributed to the development and maintenance of the nf-core/scrnaseq pipeline, focusing on integrating various single-cell RNA-Seq tools. Their contributions included adding support for different 10x Genomics barcode whitelists and integrating STAR and Kallisto alignment tools. They also worked on the structure and implementation of the pipeline, adding software versioning and integrating multiqc reporting.
nf-core10xrnaseqpipelinegenomics-data
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Olga Botvinnik - Founder at Seanome