Olga Botvinnik is a computational biologist and founder with 14 years of experience building open genomics tools that bridge single-cell transcriptomics, comparative evolution, and reproducible bioinformatics. She holds a PhD in single-cell RNA-sequencing and led cross-species “dark matter” transcriptome analyses at CZ Biohub, producing an openly available draft manuscript and tools for translating RNA reads into protein-coding sequence. Olga is an active open-source maintainer and creator—contributing to high-profile projects like nf-core, seaborn, and sourmash while authoring popular libraries such as Sencha and prettyplotlib. She blends hands-on pipeline and DevOps expertise (Nextflow, Docker, AWS) with mentorship and community outreach, from running coding clinics to a bioinformatics Twitch channel. Now based in San Francisco, she’s applying that toolkit to unlock discoveries from ocean biodiversity as founder of Seanome.
14 years of coding experience
11 years of employment as a software developer
S.B. S.B. Mathematics Biological Engineering, S.B. S.B. Mathematics Biological Engineering at Massachusetts Institute of Technology
University of California, San Diego
International Baccalaureate Diploma, International Baccalaureate Diploma at South Eugene High School
Contributions:202 commits, 1 comment in 1 year 2 months
Contributions summary:Olga's contributions primarily focused on enhancing the prettyplotlib library by adding new functionalities related to plotting. They added the ability to annotate bar plots and provided new options for gridlines within histogram plots. The user was also involved in fixing layout issues, adjusting text colors, and addressing conflicts related to plotting commands.
A single-cell RNAseq pipeline for 10X genomics data
Role in this project:
Back-end Developer & DevOps Engineer
Contributions:2 reviews, 61 commits, 3 PRs in 1 month
Contributions summary:Olga primarily contributed to the development and maintenance of the nf-core/scrnaseq pipeline, focusing on integrating various single-cell RNA-Seq tools. Their contributions included adding support for different 10x Genomics barcode whitelists and integrating STAR and Kallisto alignment tools. They also worked on the structure and implementation of the pipeline, adding software versioning and integrating multiqc reporting.
nf-core10xrnaseqpipelinegenomics-data
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