Paul Gueguen

Bioinformatician Single Cell Analysis And Spatial Transcriptomics

Lausanne, Vaud, Switzerland
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Summary

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Senior
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Top School
Paul Gueguen is a bioinformatician specializing in single-cell and spatial transcriptomics with eight years of experience at the intersection of immunology and computational biology. He holds a PhD in T cell tumor-immunology and has translated that expertise into both academia and industry, from mapping half a million tumor-infiltrating lymphocytes to contributing to preclinical CAR-T development. At ETH Zürich he delivers reproducible, scalable analyses and advises researchers on experimental design while teaching RNA-seq and mentoring students. Proficient in multi-omics integration, scRNA/scTCR workflows and spatial platforms (Xenium/VisiumHD), he combines strong R-based pipeline development with FAIR, well-documented outputs. Known for making large reference resources openly available, he blends curiosity—summed up in his GitHub tagline "Trying to understand cells"—with a pragmatic focus on actionable biological insights.
code8 years of coding experience
job1 year of employment as a software developer
bookBachelor of Science - BS Cellular biology and physiology, Bachelor of Science - BS Cellular biology and physiology at Université de Bretagne Occidentale
bookMaster of Science - MS Bioinformatics, Master of Science - MS Bioinformatics at Université de Rennes I
bookDoctor of Philosophy - PhD Immunology / Bioinformatics, Doctor of Philosophy - PhD Immunology / Bioinformatics at Université Paris Cité
bookMaster of Science - MS Bioinformatics - Master GENIOMHE (GENomics Informatics and Mathematics for Health and Environment), Master of Science - MS Bioinformatics - Master GENIOMHE (GENomics Informatics and Mathematics for Health and Environment) at Université Paris-Saclay
languagesFrench, English
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Github Skills (20)

single-cell-genomics10
bioinformatics10
genomics10
cran10
single-cell-analysis8
sequencing8
projection8
meta8
next-generation-sequencing8
transcriptomics7
atlas6
shell5
profiling5
kernel-density2
weighted2

Programming languages (3)

RCRuby

Github contributions (5)

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carmonalab/scGate_models

Jul 2022 - Dec 2022

Contributions:1 release, 79 commits, 57 pushes in 4 months
Contributions:35 commits, 19 pushes in 3 months
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Paul Gueguen - Bioinformatician Single Cell Analysis And Spatial Transcriptomics