Paul Tang
Co-founder at AccuraGen
San Francisco, California, United States
Summary
👤
Senior🎓
Top SchoolPaul Tang is a co-founder and technical leader with 12 years' experience at the intersection of genomics and diagnostics, currently leading AccuraGen’s product development and market strategy to improve rare allele detection in cell-free DNA. He built and managed high-throughput Illumina operations and informatics at UCSF—overseeing 3 HiSeqs, SOPs, LIMS, and large-scale studies—before translating that bench-to-business expertise into a startup. A PhD geneticist and former postdoc, he has co-authored a dozen+ papers and engineered cost-efficient targeted sequencing approaches and visualization workflows. Paul also contributes to open-source genomics tooling (notably enhancements to the widely used bcbio-nextgen pipeline for RNA‑seq and fusion detection), reflecting hands-on backend skills in production bioinformatics. He combines scientific rigor, operational scaling experience, and commercial insight into regulatory and reimbursement landscapes—an uncommon blend that accelerates clinical assay translation.
12 years of coding experience
3 years of employment as a software developer
The University of Hong Kong (HKU)
Github Skills (5)
rna-seq10
bioinformatics10
python10
bam9
documentation7
Programming languages (1)
Github contributions (4)
bcbio/bcbio-nextgen
Jul 2013 - Jun 2014
Validated, scalable, community developed variant calling, RNA-seq and small RNA analysis
Role in this project:
Backend Developer
Backend DeveloperContributions:16 commits, 12 comments, 7 issues in 10 months
Contributions summary:Paul primarily contributed to the bcbio-nextgen pipeline by implementing and modifying core functionalities related to RNA-seq analysis. Their work included adding support for fusion transcript detection using the Oncofuse tool, refining the handling of FASTQ/BAM files and pair identification, and modifying file paths. The user also addressed issues with installation and output visualization within the documentation.
scalablecallingrnaseqvariant-callinggenomics
chapmanb/cloudbiolinux
Sep 2013 - Dec 2013
CloudBioLinux: configure virtual (or real) machines with tools for biological analyses
Contributions:2 commits in 4 months
analysesmachinesbioinformaticsconfigurebiological
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