Prabhat KC

Senior Staff Fellow at FDA

Silver Spring, Maryland, United States
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Summary

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Prabhat KC is a Senior Staff Fellow at the US FDA with nine years of experience at the intersection of imaging physics, inverse problems, and machine learning for medical imaging. He leads projects evaluating stability and hallucination risks in AI-based reconstruction algorithms, and develops both physics-based and AI-driven methods for reconstruction, denoising, super-resolution and compressed sensing across CT, MRI, PET and ultrasound. Prabhat combines rigorous task-based and bench evaluation (NPS, MTF, numerical observers) with regulatory review experience—assessing 510(k), IDE and related submissions—to bridge research, validation, and clinical device deployment. He has collaborated with national labs and academia to create synthetic data, virtual phantoms, and objective performance tests, and organized community challenges such as the AAPM 2023 Deep Generative Modeling competition. With a PhD from Carnegie Mellon and a background in mathematics, he brings a rare mix of theoretical rigor, practical code development (PyTorch/Python/C/Octave), and regulatory insight that de-risks adoption of emerging AI in medical imaging.
code9 years of coding experience
job4 years of employment as a software developer
bookMASS (Mathematical Advanced Study Semester), Mathematics, MASS (Mathematical Advanced Study Semester), Mathematics at Penn State University
bookBachelor’s Degree, Mathematics, Bachelor’s Degree, Mathematics at Mercyhurst University
bookDoctor of Philosophy (Ph.D.), Materials Science, Doctor of Philosophy (Ph.D.), Materials Science at Carnegie Mellon University
languagesEnglish, Nepali, Hindi
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Github Skills (18)

keras10
baidu10
spark9
keras-tensorflow9
pytorch9
mpi9
mxnet9
correlation9
ray9
ring8
deep-learning8
tensorflow8
machine-learning8
image-resolution8
apache7

Programming languages (2)

Jupyter NotebookPython

Github contributions (5)

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prabhatkc/mpi4py_patches

Aug 2020 - Mar 2024

mpi4py based feature extraction/patch generation for deep learning applications of CT-images
Contributions:1 release, 2 PRs, 41 pushes in 3 years 6 months
pytorchpatch-extractionextractionpatchfeature-extraction
prabhatkc/siFRC

Oct 2019 - Jun 2020

Python implementation of the Fourier Ring Correlation (FRC) to determine image resolution
Contributions:1 release, 13 commits, 2 PRs in 7 months
pythonringpython-implementationjupyter-notebookresolution
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Prabhat KC - Senior Staff Fellow at FDA