Rachel Pyke is a bioinformatics leader with 11 years of experience merging computational rigor and practical product delivery, now serving as Director of Bioinformatics Science at Personalis. She holds a CS/Bioinformatics degree magna cum laude from UCSD and is completing a Ph.D. focused on computational cancer immunology in the Carter Lab, where she built high-throughput pipelines to analyze billions of protein interactions and assess immune-related cancer risk. Her career spans industry and research—from an Illumina internship and multiple roles at Personalis to data science work at Noah Basketball—demonstrating fluency in machine learning, large-scale genomic pipelines, and translating complex analyses into actionable insights. She has presented basketball analytics at high-profile venues and quietly applies that same experimental curiosity to immunogenomics and grant writing. Based in San Diego, she combines technical depth with leadership experience scaling teams and pipelines for clinical-grade bioinformatics.
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