Robert Policastro
Manager, Bioinformatics
Cambridge, Massachusetts, United States
Summary
👤
Senior🎓
Top SchoolRobert Policastro is a bioinformatics leader with eight years of experience building scalable NGS pipelines and regulatory-ready analyses for gene and cell therapy programs. Currently managing Bioinformatics for MaxCyte’s SeQure platform, he drives computational strategies for on/off-target editing and genomic safety using assays like GUIDE-seq and ONE-seq while ensuring FDA-aligned, reproducible reporting. Previously he stood up the computational backbone for in vivo gene editing at Ensoma and led genomics and single-cell projects at eGenesis to de-risk xenotransplantation assets. A PhD developer of STRIPE-seq and an R package for TSS analysis, he blends method development with production engineering across Illumina, 10X, and Nanopore data. Comfortable from awk to Rust, he pairs hands-on coding with mentoring and CRO partnerships to translate complex genomics into actionable program decisions. Based in Cambridge, MA, he’s an active community helper on forums like Biostars and Stack Overflow, reflecting a commitment to open scientific exchange.
8 years of coding experience
6 years of employment as a software developer
Doctor of Philosophy - PhD, Molecular Biology and Bioinformatics, Doctor of Philosophy - PhD, Molecular Biology and Bioinformatics at Indiana University BloomingtonBachelor's degree, Biology, General, Bachelor's degree, Biology, General at University of RochesterMaster of Science - MS, Biochemistry and Cell Biology, Master of Science - MS, Biochemistry and Cell Biology at Stony Brook University
Github Skills (57)
seq9
genomics8
bioinformatics7
region7
differential-expression6
transcription6
tsne6
chip-seq6
rna-seq5
bioconductor5
hierarchical-clustering5
sarif5
sequence-analysis5
nmf4
retrieval4
Programming languages (7)
Github contributions (5)
rpolicastro/tsrexplorer
Aug 2019 - Oct 2020
Contributions:2 PRs, 357 pushes, 7 branches in 1 year 3 months
rpolicastro/RNAseq
Feb 2019 - Mar 2021
Contributions:12 commits, 58 pushes, 3 branches in 2 years
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