Roberto Spreafico is a senior data science and biologics AI leader with 15+ years applying computational and wet-lab immunology expertise to drive discovery through translational stages. He has pioneered AI-driven antibody engineering since 2021, contributing to high-impact publications, patents, and invited talks while leading teams through IPOs and rapid organizational change. His work underpinned the computational efforts behind Sotrovimab, a monoclonal antibody granted emergency use authorization, and he has repeatedly accelerated developability and lead-optimization workflows with production-ready ML models. Skilled at operating in complex matrix environments, he combines hands-on pipeline and cloud infrastructure delivery with people leadership across biotech and pharma. Notably, he couples formal immunology training and wet-lab experience with deep bioinformatics chops, enabling unusually effective collaboration between experimentalists and AI teams. Now based in the UK, he scales enterprise AI strategies for biologics discovery while maintaining an active record of translational impact.
11 years of coding experience
13 years of employment as a software developer
Doctor of Philosophy - PhD, Translational and Molecular Medicine (specializing in Immunology), Doctor of Philosophy - PhD, Translational and Molecular Medicine (specializing in Immunology) at Università degli Studi di Milano-Bicocca
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Roberto Spreafico - Senior Director, Biologics AI Innovation