Saber H

Computational Scientist

Vancouver, British Columbia, Canada
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Summary

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Senior
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Top School
Saber H is a computational scientist with 11 years of experience at the intersection of AI and biology, now building virtual cell foundation models and multi-omics perturbation frameworks at Genentech. He holds a PhD in Bioinformatics from UBC and previously led foundation-model research and long-read RNA-seq work at BC Cancer, where he authored NanoSim — a widely used simulator with 23 releases, 270+ stars, and 56k+ downloads. His background spans multimodal integration, causal inference, and representation learning for biomarker discovery and patient stratification, grounded in hands-on perturbation and RNA–protein studies from his time at METU. Saber blends rigorous academic training with production-oriented open-source tooling, emphasizing reproducible computational experiments. He’s notable for translating complex sequencing innovations into practical simulation and modeling tools that accelerate biological discovery. Based in Vancouver, he combines deep domain expertise with a track record of shipping community-impacting software.
code10 years of coding experience
job11 years of employment as a software developer
bookDoctor of Philosophy - PhD, Bioinformatics, Doctor of Philosophy - PhD, Bioinformatics at The University of British Columbia
bookMaster's degree, Bioinformatics, Master's degree, Bioinformatics at Orta Doğu Teknik Üniversitesi / Middle East Technical University
languagesEnglish, Turkish
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Stackoverflow

Stats
11reputation
2kreached
1answer
0questions
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Github Skills (20)

simulation10
genome10
simulator10
structural-variation10
pairwise10
genomics10
sequence10
sequence-alignment9
bioinformatics9
save6
machine-learning6
python6
linux5
conda5
package-management4

Programming languages (2)

CPython

Github contributions (5)

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SaberHQ/NanoSim

Apr 2018 - Apr 2022

Nanopore sequence read simulator
Contributions:2 PRs, 40 pushes in 4 years
simulatorsequencenanoporesimulation
bcgsc/ntEmbd

Oct 2021 - Mar 2025

Deep learning embedding for nucleotide sequences
Contributions:1 release, 1 PR, 58 pushes in 3 years 6 months
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Saber H - Computational Scientist