Sai Chen

Principal Bioinformatician

San Diego, California, United States
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Summary

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Senior
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Top School
Sai Chen is a Principal Bioinformatician with 11 years of experience translating complex genomics data into robust clinical and research-ready solutions. With a PhD in Biomathematics/Bioinformatics from the University of Michigan and roles across Illumina, Guardant Health, and now CareDx, he blends deep statistical training with hands-on bioinformatics engineering to drive assays and pipelines from concept to production. He has advanced through individual-contributor and staff-level positions developing scalable variant-calling and NGS analytics for diagnostics, bringing both rigorous research instincts and product-focused delivery. Based in San Diego, Sai maintains an academic profile (Google Scholar) that complements his industry impact, reflecting a rare combination of published research and operationalizing genomics in clinical settings.
code11 years of coding experience
job13 years of employment as a software developer
bookDoctor of Philosophy (PhD), Biomathematics, Bioinformatics, and Computational Biology, Doctor of Philosophy (PhD), Biomathematics, Bioinformatics, and Computational Biology at University of Michigan
bookBachelor of Science (B.S.), Biology/Biological Sciences, General, Bachelor of Science (B.S.), Biology/Biological Sciences, General at Peking University
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Github Skills (18)

genome10
structural-variation10
htslib10
variants9
next-generation-sequencing9
sequencing9
infectious-diseases9
sequence9
blast8
bioinformatics7
graph7
python7
genomics7
bioconda6
polaris6

Programming languages (1)

C++

Github contributions (5)

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traxexx/Raremetal

Apr 2015 - Jul 2017

Contributions:3 releases, 26 commits, 22 pushes in 2 years 2 months
traxexx/Raremetal2

Jun 2017 - Sep 2017

Contributions:6 commits, 5 pushes, 2 branches in 2 months
updatedmetasoftware-analysismeta-analysis
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Sai Chen - Principal Bioinformatician