Sam Hesson

Engineering Manager (Agentic Systems) at Nanome

Seattle, Washington, United States
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Summary

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Senior
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Top School
Sam Hesson is an engineering leader and founder with 13 years of experience building AI-driven scientific tools, currently managing Meta’s Agentic Systems incubation team while advising and co-leading Nanome’s push into XR and molecular design. He invented and scaled multi-agent platforms for chemistry and bioinformatics—solving tool orchestration, observability, and enterprise-grade security challenges to enable scientists to chat with agents, run simulations, and collaborate in spatial computing. As Nanome’s CTO he shipped NanomeAI and MARA, a real-time, multi-agent scientific informatics platform used by hundreds of institutions across pharma, materials, and other industries. Sam blends deep product and engineering management with hands-on systems design, and his background includes GE’s software leadership program and founding a university VR club that seeded XR talent—an early signal of his knack for translating emerging interfaces into practical research workflows.
code12 years of coding experience
job14 years of employment as a software developer
bookUniversity of California, San Diego
bookSierra College
bookClayton Valley Charter High School
bookUC CAI CA BRAID NSF I-CORPS Entrepreneurship Center at UCSF, UC CAI CA BRAID NSF I-CORPS Entrepreneurship Center at UCSF at University of California, San Francisco
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Github Skills (63)

simulation10
mathematical10
plugin10
ethereum10
blockchain10
python-lib10
modeling10
computational-chemistry9
golang9
go9
api9
chemistry9
p2p9
python8
abi8

Programming languages (7)

C#ShellJavaScriptGoLuaJupyter NotebookPython

Github contributions (5)

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matryx/MatryxDocs

Apr 2018 - Feb 2019

Contributions:10 pushes in 10 months
nanome-ai/nanome-docs

Jul 2019 - Jan 2025

Documentation for Nanome (https://docs.nanome.ai)
Contributions:3 reviews, 9 PRs, 50 pushes in 5 years 7 months
deep-learningpytorchmachine-learningnanome
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Sam Hesson - Engineering Manager (Agentic Systems) at Nanome