Sam Hesson is an engineering leader and founder with 13 years of experience building AI-driven scientific tools, currently managing Meta’s Agentic Systems incubation team while advising and co-leading Nanome’s push into XR and molecular design. He invented and scaled multi-agent platforms for chemistry and bioinformatics—solving tool orchestration, observability, and enterprise-grade security challenges to enable scientists to chat with agents, run simulations, and collaborate in spatial computing. As Nanome’s CTO he shipped NanomeAI and MARA, a real-time, multi-agent scientific informatics platform used by hundreds of institutions across pharma, materials, and other industries. Sam blends deep product and engineering management with hands-on systems design, and his background includes GE’s software leadership program and founding a university VR club that seeded XR talent—an early signal of his knack for translating emerging interfaces into practical research workflows.
12 years of coding experience
14 years of employment as a software developer
University of California, San Diego
Sierra College
Clayton Valley Charter High School
UC CAI CA BRAID NSF I-CORPS Entrepreneurship Center at UCSF, UC CAI CA BRAID NSF I-CORPS Entrepreneurship Center at UCSF at University of California, San Francisco
Contributions:3 reviews, 9 PRs, 50 pushes in 5 years 7 months
deep-learningpytorchmachine-learningnanome
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Sam Hesson - Engineering Manager (Agentic Systems) at Nanome