Sandeep Somani
Co-Founder, CTO at Pinnacle Medicines
Greater Philadelphia United States
Summary
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Senior🎓
Top SchoolSandeep Somani is a computational chemist and technology leader with 14 years’ experience applying statistical mechanics, biomolecular modeling and high-performance computing to both biologics and small-molecule drug discovery. As Co-Founder and CTO of Pinnacle Medicines after a long tenure at Janssen, he combines hands-on CADD expertise—antibody engineering, vaccine and formulation design, flexible structure-based ligand modeling and free-energy simulations—with strategic due diligence and partnership building for POC studies. His academic background (PhD Chemical Physics, postdoc at Cambridge) underpins algorithm development for enhanced MD sampling and binding thermodynamics, and he routinely mentors students and postdocs. Notably, he brings an uncommon cross-disciplinary fluency: translating deep theoretical methods into practical developability assessments and formulation insights that de-risk early biologics programs.
14 years of coding experience
16 years of employment as a software developer
MD Computational Engineering, MD Computational Engineering at Singapore-MIT AllianceB.Tech. Mechanical Engg, B.Tech. Mechanical Engg at Indian Institute of Technology, GuwahatiPhD Chemical Physics, PhD Chemical Physics at University of Maryland
Github Skills (3)
landscape4
energy3
optimization2
Github contributions (1)
js850/PyGMIN
May 2012 - Mar 2013
Contributions:61 commits in 10 months
optimizationenergyglobal-optimizationlandscape
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