Sarah Pyfrom

Senior Research Project Administrator

Philadelphia, Pennsylvania, United States
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Summary

👤
Senior
🎓
Top School
Sarah Pyfrom is a molecular geneticist and bioinformatician with 11+ years translating complex genomics questions into reproducible, publication-ready results across academic and clinical research settings. She builds and maintains high-throughput NGS pipelines (RNA-seq, ATAC-seq, CUT&RUN, Hi-C), integrates multi-omics datasets, and develops tools for variant and regulatory element function prediction—most notably PLAIDOH for lncRNA functional inference. Comfortable at the bench and in code, she combines experimental design, Python/R/SQL programming, and HPC workflow deployment to take projects from concept to peer-reviewed publication. Her work contributed to journals including Cell Reports, PNAS, and Immunity, and she is focused on applying genomics to precision medicine, diagnostics, and drug discovery in collaborative, mission-driven teams. Currently based in Philadelphia, she seeks remote or hybrid roles where end-to-end project leadership and clinical variant annotation skills accelerate translational impact.
code11 years of coding experience
job6 years of employment as a software developer
bookDoctor of Philosophy - PhD, Molecular Genetics and Genomics, Doctor of Philosophy - PhD, Molecular Genetics and Genomics at Washington University in St. Louis School of Medicine
bookBachelor of Science (B.S.), Biology (Genomics), Bachelor of Science (B.S.), Biology (Genomics) at Davidson College
bookHigh School Diploma, High School Diploma at The Taft School
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Github Skills (4)

predictive6
bioinformatics5
homebrew5
macos4

Programming languages (1)

Perl

Github contributions (3)

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sarahpyfrom/PLAIDOH

Jul 2018 - Feb 2020

Source Code for PLAIDOH LncRNA Predictive Algorithm
Contributions:32 commits, 2 PRs, 15 pushes in 1 year 7 months
predictivebioinformaticslncrna
sarahpyfrom/hello-world

Jul 2018 - Jul 2018

test run because it's been ages since I used git
Contributions:2 PRs, 2 pushes, 3 branches in 1 day
testingages
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Sarah Pyfrom - Senior Research Project Administrator