Sébastien Lelong

Principal Scientific Software Engineer at Genentech

San Francisco, California, United States
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Summary

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Senior
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Sébastien Lelong is a Principal Scientific Software Engineer with 12+ years building high-throughput, cloud-native backend systems for biotech and finance, currently designing Genentech’s ArtifactDB to make genomics datasets reliably available as self-service data products. He brings deep Python expertise in concurrent programming, API design and network protocols, and has a strong track record architecting scalable AWS solutions (S3, EKS, RDS, DynamoDB, OpenSearch, IAM) with CI/CD and IaC. Previously he led Biothings APIs at Scripps, optimizing pipelines from multi-week to hourly runs and enabling public, highly-trafficked bioinformatics services that process billions of documents. Equally comfortable in systems, databases (MySQL, MongoDB, Elasticsearch) and operations, he has driven migrations to cloud, automated deployments, and built developer-facing platforms to increase contributions and reproducibility. Known for pragmatic automation and data-first design, he often combines research-minded ML prototyping with production-grade engineering to surface non-obvious bottlenecks and scale distributed data workloads.
code12 years of coding experience
job15 years of employment as a software developer
bookDESS Genie Biologique Informatique, Biomathematics, Bioinformatics, and Computational Biology, DESS Genie Biologique Informatique, Biomathematics, Bioinformatics, and Computational Biology at Université d'Evry-Val d'Essonne
languagesEnglish
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Stackoverflow

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Github Skills (104)

variants10
python10
annotations10
api10
sdk10
translator10
high-performance10
data-annotation10
api-framework10
webservice10
bioinformatics10
bots9
docker9
google-assistant9
development-environment9

Programming languages (8)

TypeScriptCSSRustVueJavaScriptGoJupyter NotebookPython

Github contributions (5)

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biothings/mychem.info

Jun 2017 - Aug 2021

MyChem.info: A BioThings API for chemical/drug annotations
Contributions:151 commits, 11 PRs, 103 pushes in 4 years 2 months
apiannotationswebservicechemicalbiothings
biothings/biothings_studio

Mar 2018 - May 2020

Pre-configured & ready-to-use BioThings API development environment
Contributions:8 releases, 136 commits, 1 PR in 2 years 1 month
apiapi-developmentbiothingsdevelopment-environment
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Sébastien Lelong - Principal Scientific Software Engineer at Genentech