Semion Leyn is a Senior Bioinformatics Scientist based in Chicago with over a decade of experience translating complex NGS data into actionable biological insights across academic and industrial settings. He specializes in variant calling and population-level genomic analysis using Illumina and Oxford Nanopore data, and pioneered workflows that combine morbidostat-driven evolution experiments with clonal sequencing to dissect antibiotic resistance mechanisms. His work spans metabolic and regulatory network reconstruction for microbiomes and bacteria, informed by a PhD in Biomathematics/Bioinformatics and a background in chemical biotechnology. At Agilent and Sanford Burnham Prebys he has bridged method development and applied pipelines for drug discovery and microbiome projects, demonstrating a rare blend of experimental-aware computation. Colleagues note his ability to turn bespoke experimental designs into robust, reproducible analysis pipelines that scale from single clones to evolving populations.
9 years of coding experience
12 years of employment as a software developer
Doctor of Philosophy - PhD Biomathematics Bioinformatics and Computational Biology, Doctor of Philosophy - PhD Biomathematics Bioinformatics and Computational Biology at IITP RAS
Master of Science (MSc) Chemical technology and Biotechnology, Master of Science (MSc) Chemical technology and Biotechnology at Mendeleyev University of Chemical Technology of Russia
Software to search rearrangements in population sequencing data
Contributions:149 commits, 7 PRs, 124 pushes in 3 years 8 months
bioinformaticssequencingsequencing-data
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