Shahab Sarmashghi

Postdoctoral Associate

Cambridge, Massachusetts, United States
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Summary

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Shahab Sarmashghi is a postdoctoral scientist at the Broad Institute and affiliated research fellow at Harvard Medical School and Dana-Farber, applying statistical, algorithmic and mathematical frameworks to decode cancer genome rearrangements and mechanisms of therapy resistance. With eight years of experience and a PhD in Electrical and Computer Engineering from UC San Diego, he builds scalable methods for high-throughput sequencing analysis that span applications from tumor evolution to ecosystem biodiversity and food safety. His work blends rigorous modeling of genomic overlap, assembly-free analysis of low-coverage WGS, and large-scale model training across hundreds of species, enabling robust inference from noisy or sparse data. Notably, he moves comfortably between algorithm development and practical pipelines—simulating dynamic populations, estimating genome repeat content, and integrating pathology and expression data for translational cancer studies.
code8 years of coding experience
job6 years of employment as a software developer
bookUniversity of California San Diego
bookBachelor of Science (BSc), Electrical Engineering, Bachelor of Science (BSc), Electrical Engineering at Sharif University of Technology
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Github Skills (12)

bioinformatics10
conda10
genome10
package-management10
bioconda10
sequencing9
genomics9
science7
spark-ml7
gatk6
spark5
apache-spark5

Programming languages (3)

JavaShellPython

Github contributions (5)

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Conda recipes for the bioconda channel.
Contributions:28 pushes, 21 branches in 3 years 5 months
biocondabioinformaticsrecipesconda
shahab-sarmashghi/RESPECT

Nov 2020 - Dec 2022

Contributions:7 releases, 23 commits, 26 pushes in 2 years 1 month
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Shahab Sarmashghi - Postdoctoral Associate