Shiqi Xie
Principle Scientist, Technology at Genentech
South San Francisco, California, United States
Summary
👤
Senior🎓
Top SchoolShiqi Xie is a Principal Scientist in Technology at Genentech with nine years of experience at the interface of genomics, single-cell assays, and computational biology. She built and scaled Mosaic-seq and Virtual-FACS during a productive postdoc, enabling multiplexed enhancer perturbation and statistical discovery of direct and indirect regulatory targets. Her work spans experimental platform development—CRISPR libraries, single-cell RNA-seq workflows, epigenomic integration—and computational pipelines for enhancer feature identification. Based in South San Francisco, she combines hands-on lab leadership with translational focus on closing the AI-validation gap in drug discovery. Unusually for someone in technology roles, she has deep wet-lab provenance and multiple high-impact publications that reflect both method development and genome-scale analyses.
9 years of coding experience
Bachelor's Degree, Life Science, Bachelor's Degree, Life Science at Sichuan UniversityDoctor of Philosophy (Ph.D.), Virology, Doctor of Philosophy (Ph.D.), Virology at Institut Pasteur of Shanghai
Chinese, English
Github Skills (23)
structural-variation9
barcodes9
fastq9
rna-seq9
expression8
single-cell-analysis8
sequencing8
bioinformatics7
pipeline7
transcriptomics7
genomics7
nextflow6
matplotlib4
seq4
python4
Programming languages (3)
Github contributions (5)
russellxie/Global-analysis-K562-enhancers
Apr 2019 - Dec 2019
Contributions:30 commits, 28 pushes, 1 branch in 7 months
russellxie/Hon_Lab_Bioinfo_Class
Apr 2020 - Apr 2020
This is the playground for the folks in Hon lab to learn bioinformatics analysis skills
Contributions:23 commits, 1 PR, 20 pushes in 3 days
hondata-analysisdata-sciencebioinformatics-analysisbioinformatics
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