Simona Cristea
Director, Applied AI at Tempus AI
Boston, Massachusetts, United States
Summary
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Senior🎓
Top SchoolSimona Cristea is a Director of Applied AI and computational genomics leader with a decade of experience applying LLMs and multi-modal machine learning to cancer prevention, diagnostics, and treatment. She has led interdisciplinary teams at Dana-Farber and Harvard, developing novel decoder LLMs (evoCancerGPT), scGPT adaptations, and probabilistic generative models to reveal tumor evolution, spatial immunology, and mechanisms of therapy resistance. Her work spans single-cell and spatial genomics, clinical trial data integration, and CRISPR/antibody screens, translating computational discoveries into translational research pipelines. Trained at ETH Zürich with influential tools like ModulOmics and TiMEx, she combines deep theoretical pedigree with pragmatic, clinical-facing AI deployments. Based in Boston, she brings a rare blend of probabilistic modeling, evolutionary thinking, and large-language-model engineering to tackle mechanistic questions in oncology.
11 years of coding experience
7 years of employment as a software developer
Doctor of Philosophy - PhD, Computational Cancer Genomics, Doctor of Philosophy - PhD, Computational Cancer Genomics at ETH Zürich
Stackoverflow
1reputation
0reached
0answers
0questions
Github Skills (9)
bioconductor8
cran6
bayesian4
bioinformatics4
transcriptomics3
single-cell-genomics3
ppi3
single-cell-analysis3
rna-seq2
Programming languages (2)
Github contributions (5)
cbg-ethz/TiMEx
Jul 2015 - Nov 2018
Bioconductor package for finding mutually exclusive groups of alterations in large cancer datasets
Contributions:50 commits, 11 PRs, 24 pushes in 3 years 4 months
bioconductor
Michorlab/tnbc_scrnaseq
Aug 2018 - Oct 2018
Contributions:51 commits, 8 PRs, 40 pushes in 1 month
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