Skyler Kuhn

Bioinformatics Analyst II

Washington DC-Baltimore Area United States
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Summary

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Senior
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Top School
Skyler Kuhn is a Bioinformatics Analyst II with a decade of experience designing, implementing, and operating scalable, fault-tolerant bioinformatics pipelines for high-performance and cloud environments. At Leidos supporting the NCI, he specializes in transcriptomics—building and benchmarking workflows for gene expression, isoform regulation, alternative splicing, viral integration, RNA–RNA interactions, and RNA secondary structure—and serves as a go-to analyst and guest lecturer on RNA-seq best practices. He has led migrations of complex on-premise pipelines to the cloud and supports end-to-end project lifecycles from raw data to manuscript co-authorship. With a strong computational foundation (M.S. in Bioinformatics, 3.9 GPA) and prior roles in scientific programming, teaching, and database-driven web apps, he blends rigorous research literacy with production-grade software engineering. Outside the lab, he balances technical depth with real-world curiosity—hinted by a leadership role on GitHub and a fondness for adding one more bike to the fleet.
code10 years of coding experience
bookMaster's degree, Bioinformatics, 3.9, Master's degree, Bioinformatics, 3.9 at Virginia Commonwealth University
bookBachelor of Science, Biology/Biological Sciences, General, Bachelor of Science, Biology/Biological Sciences, General at James Madison University
languagespython, r, bash, sql, java
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Github Skills (190)

snakemake10
seq10
gene-expression10
genomics10
spark-ml10
singularity10
rna-seq10
fasta10
aggregate10
genome10
sequencing10
pypi10
chip-seq10
fastq10
bioinformatics10

Programming languages (19)

JavaC++CSSCScalaVueGoPerl

Github contributions (5)

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OpenOmics/mr-seek

Dec 2022 - Mar 2025

Mendelian Randomization pipeline
Contributions:2 releases, 1 review, 1 PR in 2 years 4 months
snakemakemendelian-randomizationpipelinerandomization
CCBR/HERVx

Sep 2020 - Apr 2022

Pipeline to characterize Human Endogenous Retrovirus (HERV) expression
Contributions:30 commits, 4 PRs, 18 pushes in 1 year 7 months
pipelinedockergenomicswdl-workflowbioinformatics
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Skyler Kuhn - Bioinformatics Analyst II