Soroush Samadian

Senior Director, Bioinformatics

United States
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Summary

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Senior
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Top School
Soroush Samadian is a senior bioinformatics leader with a PhD in Biomathematics and 15+ years driving clinical genomics and precision medicine across companies like GeneDx, Guardant Health, Ambry, and NeoGenomics. He combines deep domain expertise in somatic and germline pipelines with hands-on engineering—launching cloud-native WES/WGS pipelines, MLOps on AWS, and automated drift detection to improve quality and reduce costs. His work has repeatedly cut turnaround times and COGS (examples include 60–80% TAT reductions and major CNV confirmation improvements) while maintaining CAP/CLIA and regulatory rigor. Soroush blends research and product impact from a postdoc in cancer genomics to industry-scale deployments, and has published methods for CNV-driven tumor evolution and benchmarking. Known for building high-performance, cross-functional teams, he emphasizes mentorship, empathy, and operationalizing AI/ML in regulated settings. An often overlooked strength is his background in electrical engineering and early large-scale data engineering experience, which gives him a practical systems view when scaling bioinformatics infrastructure.
code9 years of coding experience
job5 years of employment as a software developer
bookDoctor of Philosophy (PhD) Biomathematics Bioinformatics and Computational Biology, Doctor of Philosophy (PhD) Biomathematics Bioinformatics and Computational Biology at The University of British Columbia
bookMaster of Science (MSc) Computer Systems Networking and Telecommunications, Master of Science (MSc) Computer Systems Networking and Telecommunications at The University of Sheffield
bookBachelor of Science (BSc) Electrical and Electronics Engineering, Bachelor of Science (BSc) Electrical and Electronics Engineering at Sharif University of Technology
languagesEnglish, Persian, Spanish, Italian
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Github Skills (2)

sequence10
bioinformatics10

Programming languages (1)

Python

Github contributions (3)

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pughlab/bamgineer

Jan 2017 - Apr 2018

Bamgineer: Introduction of simulated allele-specific copy number variants into exome and targeted sequence data sets
Contributions:358 commits, 7 PRs, 312 pushes in 1 year 3 months
sequencedata-setsexomebioinformaticsallele
soroushsamadian/bamgineer

Jan 2017 - Mar 2017

Contributions:24 pushes, 4 branches in 2 months
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Soroush Samadian - Senior Director, Bioinformatics