Stephen Williams
Staff Scientist at 10x Genomics
Greater Charlottesville Area United States
Summary
👤
Senior🎓
Top SchoolStephen Williams is a Staff Scientist and developer ecosystem lead at 10x Genomics with nine years of experience translating genomics research into product-ready computational tools. He combines deep wet-lab expertise—from CRISPR to metabolomics—with strong quantitative skills in R, Unix, AWS and bioinformatics, enabling cross-functional work across molecular biology, software, and computational biology teams. Formerly an Assistant Professor of Neurology, he led translational projects on genetic and epigenetic drivers of cerebrovascular disease and biomarker discovery. An active open-source contributor, he significantly extended spatial genomics support in the widely used Seurat toolkit (Read10xSpatial and Spaceranger compatibility), reflecting a focus on reproducible, interoperable tools. He is passionate about open science and building practical, validated solutions that bridge academia, industry, and clinical translation.
9 years of coding experience
10 years of employment as a software developer
Doctor of Philosophy (Ph.D.) Human and Molecular Genetics, Doctor of Philosophy (Ph.D.) Human and Molecular Genetics at Virginia Commonwealth University School of MedicineBachelor's Degree Integrated Science and Technology with a focus in Biotechnology, Bachelor's Degree Integrated Science and Technology with a focus in Biotechnology at James Madison University
English
Github Skills (5)
rna-seq10
dplyr10
r10
ggplot9
bioinformatics9
Programming languages (8)
Github contributions (5)
satijalab/seurat
Sep 2019 - Jul 2022
R toolkit for single cell genomics
Role in this project:
Back-end Developer & Data Scientist
Back-end Developer & Data ScientistContributions:6 reviews, 7 commits, 2 PRs in 2 years 10 months
Contributions summary:Stephen contributed significantly to the `seurat` R toolkit, primarily focusing on implementing spatial genomics functionalities. Their work includes creating a function, `Read10xSpatial`, to read spatial data and integrating the dplyr package for data manipulation. The user also added plotting functions and made modifications to accommodate different versions of the spatial data format, demonstrating their involvement in improving the tool's usability and compatibility. Furthermore, they improved compatibility with the spaceranger 2.0 and 2.1 updates.
single-cell-genomicscranhuman-cell-atlasgenomicsbioinformatics
stephenwilliams22/single-cell-3prime-snp-clustering
Jan 2018 - Apr 2018
Contributions:5 PRs, 204 pushes, 5 branches in 2 months
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