Stephen Wyka
Senior Scientist, Genomics at LifeMine Therapeutics
Auburn, New Hampshire, United States
Summary
👤
Senior🎓
Top SchoolStephen Wyka is a Senior Scientist in Genomics with nine years of experience applying computational biology to natural product drug discovery, microbial genomics, and multi-omics integration. He builds and optimizes cloud-native (AWS/GCP) pipelines and scalable pangenome/orthology platforms that have processed 100,000+ genomes and cut infrastructure costs by over 85%, directly enabling discovery of therapeutic candidates now in clinical development. His work blends algorithm development, ML (including transformer-based fine-tuning and XGBoost classifiers), and mass-spec/genotype linking—he even developed a molecule-clustering approach that shortened analytical interpretation timelines by 30%. A hands-on mentor and cross-functional collaborator, he partners with microbiology, synthetic biology, and analytical chemistry teams to move genomic insights into fermentation and molecule retrieval workflows. Trained as a plant pathologist (PhD) with extensive fungal genomics and MS experience, he uniquely pairs deep domain biology with production-grade software engineering and a public GitHub portfolio.
8 years of coding experience
3 years of employment as a software developer
Don Bosco Preparatory High SchoolDoctor of Philosophy - PhD Plant Pathology, Doctor of Philosophy - PhD Plant Pathology at Colorado State UniversityMaster of Science (MSc) Plant Biology, Master of Science (MSc) Plant Biology at University of New Hampshire
Stackoverflow
323reputation
12kreached
1answer
4questions
Github Skills (81)
genome-annotation10
seq9
genome-assembly9
comparative-genomics9
population-genetics9
genome9
rna-seq8
next-generation-sequencing8
genomics8
gene-expression8
illumina8
bioinformatics8
sequencing8
nmf7
transcript7
Programming languages (5)
Github contributions (5)
PlantDr430/FunFinder_Pangenome
Sep 2019 - May 2020
Contributions:31 commits, 2 pushes in 8 months
PlantDr430/TransposableELMT
Jun 2019 - Mar 2020
Contributions:1 release, 23 commits, 22 pushes in 9 months
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