Steve Lianoglou

Director, Translational Genomics

San Francisco, California, United States
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Summary

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Steve Lianoglou is Director of Translational Genomics with 17 years blending computational biology, machine learning, and bioinformatics to accelerate therapeutic discovery in neurodegeneration and oncology. He leads cross-functional wet/dry teams and builds modular, user-friendly open-source tooling (facile.bio) that helps both bench and computational scientists explore single-cell and functional genomics. His work spans industry and academia—from a PhD in computational biology at Weill Cornell to leadership roles at Genentech, Denali, and ReviR—delivering genomics-driven programs and lab-focused bioinformatics. An experienced R developer, he contributed notable enhancements to the widely used data.table package, improving merge semantics and S4 compatibility. Pragmatic and collaborative, he favors interactive ecosystems that increase scientific throughput while keeping advanced statistical rigor accessible to non-programmers.
code17 years of coding experience
job13 years of employment as a software developer
bookBSc Computer Science, BSc Computer Science at Binghamton University
bookMSc Computer Science, MSc Computer Science at Columbia Engineering
bookPhD Computational Biology, PhD Computational Biology at Weill Cornell Medical College, Cornell University
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Github Skills (17)

r10
package-development10
data-structure10
data-structures10
testing9
statistic9
append9
statistics9
package9
emacs9
return-value9
ido6
assign6
svm6
dataframe6

Programming languages (12)

TypeScriptDockerfileRShellC++RustCTeX

Github contributions (5)

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Rdatatable/data.table

Feb 2011 - Dec 2013

R's data.table package extends data.frame:
Role in this project:
userBack-end Developer
Contributions:37 commits, 3 comments in 2 years 9 months
Contributions summary:Steve primarily contributed to the `data.table` package, focusing on enhancing the `merge` functionality. They implemented new features like the `by` and `suffixes` arguments, improving compatibility with `merge.data.frame`. The user also addressed bug fixes related to these features, ensuring correct column naming, and added tests to validate the behavior of the `merge` function. Additionally, they incorporated S4 compatibility and related documentation updates.
r-packageframecranrrstats
denalitherapeutics/archs4

Mar 2018 - Sep 2018

Contributions:45 commits, 14 pushes, 1 issue in 5 months
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