Tianshi Lu

Senior Scientist at Genentech

South San Francisco, California, United States
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Summary

👤
Senior
🎓
Top School
Tianshi Lu is a Senior Scientist at Genentech with eight years of experience applying deep learning, Bayesian modeling, and classical machine learning to computational biology and immuno-oncology. He holds a PhD from UT Southwestern and has authored work in top-tier journals such as Cell and Science Immunology, reflecting a strong track record in translational and reverse-translation research. Comfortable across R, Python, SQL and major ML frameworks (TensorFlow, PyTorch, Keras), he builds production-ready models that bridge bioinformatics, statistics, and clinical insight. His background includes modeling neoantigen clonal dynamics and immunoprotein binding, a niche that combines immunology with algorithmic rigor to predict therapy response. Based in South San Francisco, he blends academic publication pedigree with industry impact, often pushing probabilistic approaches into real-world drug discovery problems.
code8 years of coding experience
job4 years of employment as a software developer
bookDoctor of Philosophy - PhD, Doctor of Philosophy - PhD at UT Southwestern Medical Center
bookBachelor of Science - BS, Bachelor of Science - BS at Xiamen University
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Github Skills (17)

specificity10
binding10
hierarchical9
interaction9
bayesian-inference8
bayesian8
probabilistic-graphical-models8
pipeline7
deep-learning7
mutation7
genome2
bioinformatics2
genomics2
evolution2
sequencing2

Programming languages (4)

RC++CPython

Github contributions (5)

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QBRC Somatic Mutation Calling Pipeline
Contributions:1 release, 66 commits, 2 PRs in 3 years 5 months
somaticcallingmutationpipeline
Contributions:43 commits, 41 pushes, 1 tag in 3 years 5 months
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Tianshi Lu - Senior Scientist at Genentech