Tom Lyons
Co-Founder at AGI Leaf
Cambridge, Massachusetts, United States
Summary
🤩
Rockstar🎓
Top SchoolTom Lyons is a seasoned software engineer and entrepreneur with 13+ years (and deep prior experience) building high-scale, pragmatic systems from startups to research institutes. As Co-Founder of AGI Leaf and former Principal Software Engineer at the Broad Institute, he has delivered mission-critical pipelines (e.g., processing 110,000 exomes in three weeks) and has a knack for shipping solutions without perfect specs. His background spans cloud, SRE, real-time video, embedded networking, and language/runtime work, reflecting a rare blend of systems, performance, and tooling expertise. He repeatedly simplifies complexity—“simple, legible leverage on computing systems”—turning brittle stacks into reliable infrastructure. Comfortable leading, following, or getting out of the way, he pairs hands-on engineering with pragmatic leadership. Based in Cambridge, MA, he brings a long history of solving obscure low-level problems that make large systems possible.
13 years of coding experience
41 years of employment as a software developer
B.S. Physics, B.S. Physics at Washington University in St. Louis
Github Skills (80)
hts10
throughput10
bam10
fasta10
sequencing10
fastq10
java-api10
sequence10
warnings9
bioconda9
launcher9
genomics9
sam9
java9
nim-language9
Programming languages (11)
Github contributions (5)
broadinstitute/wfl
Mar 2020 - Oct 2022
WorkFlow Launcher (née Zero)
Contributions:1 release, 496 reviews, 307 commits in 2 years 8 months
launcherzeroworkflow
tbl3rd/sunshine
Aug 2014 - Sep 2014
Contributions:215 commits in 1 month
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